105080-63-5

Basic information

• Product Name: Benzoic acid, 4-[[[(4-chlorophenyl)sulfonyl]amino]carbonyl]-
• CAS NO: 105080-63-5
• Molecular Formula: C14H10ClNO5S
• Molecular Weight: 339.756
• Mol File: 105080-63-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-[[[(4-chlorophenyl)sulfonyl]amino]carbonyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-[[[(4-chlorophenyl)sulfonyl]amino]carbonyl]-(105080-63-5)
• EPA Substance Registry System: Benzoic acid, 4-[[[(4-chlorophenyl)sulfonyl]amino]carbonyl]-(105080-63-5)

Safety Data

• Hazardous Substances Data: 105080-63-5(Hazardous Substances Data)

Upstream product

• 100-20-9 terephthaloyl chloride 
• 20576-82-3 terephthalic acid mono-tert-butyl ester 
• 28313-42-0 di-tert-butyl terephthalate 
• 98-64-6 4-Chlorobenzenesulfonamide 
• 105080-62-4 tert-butyl-4-<<<(4-chlorophenyl)sulfonyl>amino>carbonyl>benzoate 

Downstream Products

• 137301-69-0 <(2R,3S)+(2S,3R)>-N-<<4-<<<(4-chlorophenyl)sulfonyl>amino>carbonyl>phenyl>oxomethyl>-L-valyl-ψ(CH2)-N-(2,3-dihydro-1H-inden-2-yl)glycine N-<3-(1,1,1-trifluoro-4-methyl-2-hydroxypentyl)>amide 
• 137301-78-1 4-(4-Chloro-benzenesulfonylaminocarbonyl)-N-{(S)-1-[({(S)-1-[hydroxy-(4-trifluoromethyl-phenyl)-methyl]-2-methyl-propylcarbamoyl}-methyl)-indan-2-yl-carbamoyl]-2-methyl-propyl}-benzamide 
• 137301-88-3 (3S,2RS)-N-<<4-<<<(4-chlorophenyl)sulfonyl>amino>carbonyl>phenyl>oxomethyl>-L-valyl-N-(2,3-dihydro-1H-inden-2-yl)glycine N-<3-(1,1,1-trifluoro-4-phenyl-2-hydroxybutyl)>amide 
• 131541-25-8 <(2R,3S)+(2S,3R)>-N-<<4-<<<(4-chlorophenyl)sulfonyl>amino>carbonyl>phenyl>oxomethyl>-L-valyl-N-(2,3-dihydro-1H-inden-2-yl)glycine N-<3-(1,1,1-trifluoro-4-methyl-2-hydroxypentyl)>amide 
• 137301-98-5 (2RS)-N-<<4-<<<(4-chlorophenyl)sulfonyl>amino>carbonyl>phenyl>oxomethyl>-L-valyl-N-(2,3-dihydro-1H-inden-2-yl)glycine N-<3-(1,1,1-trifluoro-3-methyl-2-hydroxybutyl)>amide 
• 131506-16-6 N-((S)-1-{Bicyclo[2.2.1]hept-2-yl-[(3,3,3-trifluoro-2-hydroxy-1-isopropyl-propylcarbamoyl)-methyl]-carbamoyl}-2-methyl-propyl)-4-(4-chloro-benzenesulfonylaminocarbonyl)-benzamide 
• 131506-19-9 4-(4-Chloro-benzenesulfonylaminocarbonyl)-N-((S)-1-{cyclopentyl-[(3,3,3-trifluoro-2-hydroxy-1-isopropyl-propylcarbamoyl)-methyl]-carbamoyl}-2-methyl-propyl)-benzamide 
• 105080-50-0 4-(4-chlorophenyl sulfonylcarbamoyl)benzoyl-L-valyl-L-prolyl-1-(RS)-(1-trifluoroacetyl-2-methylprolyl)amide 
• 137301-79-2 (2S)-<<4-<<<(4-chlorophenyl)sulfonyl>amino>carbonyl>phenyl>oxomethyl>-L-valyl-N-(2,3-dihydro-1H-inden-2-yl)glycine N-<2-<3-methyl-1-<4-(trifluoromethyl)phenyl>-1-oxobutyl>>amide 

Relevant articles and documents

Peptide derivatives

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Heterocyclic ketones

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PEPTIDE DERIVATIVES

The invention concerns pharmaceutically useful trifluoromethyl ketone substituted di-, tri-and tetra-peptide derivatives of the formulae Ia, Ib, Ic set out hereinafter, and salts thereof, which are inhibitors of human leukocyte elastase. Also described herein are pharmaceutical compositions containing a peptide derivative and processes and intermediates for use in the manufacture of the peptide derivatives.