105089-66-5

Basic information

• Product Name: Pyrrolidine, 1-(2-aminobenzoyl)-2-[bis(ethylthio)methyl]-, (2S)-
• CAS NO: 105089-66-5
• Molecular Formula: C16H24N2OS2
• Molecular Weight: 324.511
• Mol File: 105089-66-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Pyrrolidine, 1-(2-aminobenzoyl)-2-[bis(ethylthio)methyl]-, (2S)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrrolidine, 1-(2-aminobenzoyl)-2-[bis(ethylthio)methyl]-, (2S)-(105089-66-5)
• EPA Substance Registry System: Pyrrolidine, 1-(2-aminobenzoyl)-2-[bis(ethylthio)methyl]-, (2S)-(105089-66-5)

Safety Data

• Hazardous Substances Data: 105089-66-5(Hazardous Substances Data)

Upstream product

• 1148-11-4 N-Benzyloxycarbonyl-L-proline 
• 105089-64-3 N-(2-nitrobenzoyl)-L-proline methyl ester 
• 105089-87-0 benzyl (2S)-2-[di(ethylsulfanyl)methyl]tetrahydro-1H-1-pyrrolecarboxylate 
• 72435-94-0 (S)-N-(2-nitrobenzyl)pyrrolidine-2-carboxaldehyde 
• 18877-33-3 (S)-1-(2-nitrobenzoyl)pyrrolidine-2-carboxylic acid 
• 5211-23-4 N-carbobenzyloxy-L-proline methyl ester 
• 71461-30-8 (S)-2-formylpyrrolidine-1-carboxylic acid benzyl ester 
• 61350-60-5 (S)-benzyloxycarbonyl-proline acid chloride 
• 610-14-0 2-nitrobenzyl chloride 
• 105089-88-1 (2S)-2-[di(ethylsulfanyl)methyl]tetrahydro-1H-pyrrole 
• 105089-65-4 (2S)-N-(2-nitrobenzoyl)pyrrolidine-2-carboxaldehyde diethyl thioacetal 

Downstream Products

• 72435-89-3 (11aS)-1,2,3,11a-tetrahydro-5H-pyrrolo[2,1-c][1,4]benzodiazepin-5-one 

Relevant articles and documents

Microwave enhanced reduction of nitro and azido arenes to N-arylformamides employing Zn-HCOONH4: Synthesis of 4(3H)-quinazolinones and pyrrolo[2,1-c][1,4]benzodiazepines

Microwave mediated reduction of nitro and azido arenes to N-arylformamides using Zn-HCOONH4 is described. In the absence of microwave conditions, this methodology affords amines. This protocol has been extended to the synthesis of pyrrolo[2,1-c][1,4]benzodiazepines and 4(3H)-quinazolinones.

A versatile and efficient synthesis of carbinolamine-containing pyrrolo[1,4]benzodiazepines via the cyclization of N-(2-aminobenzoy 1)pyrrolidine-2-carboxaldehyde diethyl thioacetals: Total synthesis of prothracarcin

A versatile and efficient synthesis of carbinolamine-containing pyrrolo[1,4]benzodiazepines (or the corresponding imine forms) of types 2, 7, and 8 is described that involves mercuric chloride mediated cyclization of the corresponding N-(2-aminobenzoyl)py