105124-99-0

Basic information

• Product Name: 4-bromo-2-thiophen-3-yl-thiophene
• CAS NO: 105124-99-0
• Molecular Formula: C₈H₅BrS₂
• Molecular Weight: 245.164
• Mol File: 105124-99-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-bromo-2-thiophen-3-yl-thiophene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-2-thiophen-3-yl-thiophene(105124-99-0)
• EPA Substance Registry System: 4-bromo-2-thiophen-3-yl-thiophene(105124-99-0)

Safety Data

• Hazardous Substances Data: 105124-99-0(Hazardous Substances Data)

Upstream product

• 3140-92-9 2,4-dibromothiophene 
• 106032-16-0 3-thienylmagnesium bromide 

Relevant articles and documents

PALLADIUM-CATALYZED SYNTHESES OF BI- AND TER-THIOPHENES

Several heteropolyaromatic compounds containing thiophen rings, of general formula 2, 3, and 5, which are possible antifungal agents, have been synthesized in good yields by Pd-catalyzed reactions.In particular, cross-coupling reactions between 2- or 3-thienylmagnesium bromide and dibromothiophens of general formula 8 in the presence of catalytic amounts of PdCl2, have been used to prepare three isomers (2a, 2b, and 2c) of the naturally occurring 2,2':5',2"-terthiophen, 1, as well as several bromobithienyls of general formula 3.An analogous procedure has been employed for the regioselective synthesis of 3'-bromo-2,2':5',2"-terthiophen, 4, starting from 2-thienylmagnesium bromide, 7a, and 2,3,5-tribromothiophen, 8.On the other hand, heterocyclic esters of general formula 5, which are not readily accessible using conventional organic methods, have been conveniently prepared by Pd-catalyzed ethoxycarbonylation of bromobithienyls 3 under mild experimental conditions.A short synthesis of 5'-(1-propynyl)-2,2'-bithienyl-5-carboxylic acid, 6, a compound isolated from the roots of Arctium lappa, shows the efficacy of the reported Pd-catalyzed reactions.