105140-17-8

Basic information

• Product Name: 1-Triazene, 1-(2-furanylmethyl)-3-phenyl-
• CAS NO: 105140-17-8
• Molecular Formula: C11H11N3O
• Molecular Weight: 201.228
• Mol File: 105140-17-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-Triazene, 1-(2-furanylmethyl)-3-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Triazene, 1-(2-furanylmethyl)-3-phenyl-(105140-17-8)
• EPA Substance Registry System: 1-Triazene, 1-(2-furanylmethyl)-3-phenyl-(105140-17-8)

Safety Data

• Hazardous Substances Data: 105140-17-8(Hazardous Substances Data)

Upstream product

• 617-89-0 furan-2-ylmethanamine 
• 369-58-4 benzenediazonium hexafluorophosphate 

Relevant articles and documents

Preparation and Antitumor Activity of New Mitomycin A Analogues

A series of 26 mitomycin A analogues including 23 new ones was prepared by a variety of methods.The most useful methods were alkoxide exchange on mitomycin A and treatment of 7-hydroxymitosane with 3-substituted 1-phenyltriazenes.Many of the new analogues were superior to mitomycin C in the P388 leukemia assay and the more stringent subcutaneous B16 melanoma assay both in mice.Four of them gave long-term survivors in the latter assay.Quantitative correlations between log P and antitumor activity were not possible, but some guidelines for future analogue development are proposed.