105159-32-8

Basic information

• Product Name: Benzenesulfonamide, 4-methyl-N-[2-phenyl-2-(phenylamino)ethyl]-
• CAS NO: 105159-32-8
• Molecular Formula: C21H22N2O2S
• Molecular Weight: 366.484
• Mol File: 105159-32-8.mol
• Article Data: 17

Chemical Properties

• CAS DataBase Reference: Benzenesulfonamide, 4-methyl-N-[2-phenyl-2-(phenylamino)ethyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenesulfonamide, 4-methyl-N-[2-phenyl-2-(phenylamino)ethyl]-(105159-32-8)
• EPA Substance Registry System: Benzenesulfonamide, 4-methyl-N-[2-phenyl-2-(phenylamino)ethyl]-(105159-32-8)

Safety Data

• Hazardous Substances Data: 105159-32-8(Hazardous Substances Data)

Upstream product

• 5770-42-3 1,3-dimethyl-6-methylamino-1H-pyrimidine-2,4-dione 
• 97511-33-6 3,4-diphenyl-1-tosylimidazolidine 
• 24395-14-0 N-(p-tolylsulfonyl)-2-phenylaziridine 
• 62-53-3 aniline 
• 55962-05-5 [N-(p-tolylsulfonyl)imino]phenyliodinane 
• 127-65-1 chloroamine-T 
• 100-42-5 styrene 
• 21080-09-1 NSC 4573 
• 5770-49-0 6-(benzylamino)-1,3-dimethyluracil 
• 42164-54-5 N-(2-amino-1-phenylethyl)benzenamine 
• 98-59-9 p-toluenesulfonyl chloride 
• 7278-51-5 6-anilino-1,3-dimethyluracil 
• 6642-31-5 6-Amino-1,3-dimethylbarbituric acid 

Downstream Products

• 611232-63-4 N-(2-(benzyl(phenyl)amino)-2-phenylethyl)-4-methylbenzenesulfonamide 
• 105159-20-4 C₄₃H₄₄N₄O₄S₂ 
• 105159-28-2 N-{2-[4-(1,3-Dimethyl-2,4-dioxo-6-phenylamino-1,2,3,4-tetrahydro-pyrimidin-5-ylmethyl)-phenylamino]-2-phenyl-ethyl}-4-methyl-benzenesulfonamide 
• 105159-25-9 N-{2-[4-(6-Amino-1,3-dimethyl-2,4-dioxo-1,2,3,4-tetrahydro-pyrimidin-5-ylmethyl)-phenylamino]-2-phenyl-ethyl}-4-methyl-benzenesulfonamide 
• 105167-93-9 C₂₅H₂₆N₆O₄ 
• 97511-34-7 4-methyl-N-(2-(methyl(phenyl)amino)-2-phenylethyl)benzenesulfonamide 
• 97511-33-6 3,4-diphenyl-1-tosylimidazolidine 

Relevant articles and documents

LiClO4-catalyzed ring-opening of aziridines with aromatic amines

A variety of N-tosylaziridines undergo smoothly ring opening with aromatic amines using a catalytic amount of lithium perchlorate in acetonitrile at ambient temperature to afford the corresponding 1,2-diamines in excellent yields.

A highly efficient and general method for the ring-opening of aziridines with various nucleophiles in DMSO

Ring-opening of aziridines with various nucleophiles (such as amines, thiols, and silylated nucleophiles) in DMSO under mild conditions without any catalyst afforded the corresponding products in good to excellent yields. The Royal Society of Chemistry 20

Ring-opening reaction of aziridines with amines under the influence of dimethyl sulfoxide to dedicated to late Tomoko Kakinuma, past member in our laboratory

The ring-opening reaction of various aziridines with amines proceeded at room temperature to afford the corresponding 1,2-diamines in good to excellent yields using only 3-5 equiv dimethyl sulfoxide (DMSO) to aziridines in hexane. This reaction can be performed with easy handling and proceeds under mild reaction conditions. Also a variety of amines are available as a nucleophile.

1-Butyl-3-methylimidazolium Tetrafluoroborate ([Bmim]BF4) Ionic Liquid: A Novel and Recyclable Reaction Medium for the Synthesis of vic-Diamines

Aziridines undergo ring opening smoothly with various arylamines in 1-butyl-3-methylimidazolium tetrafluoroborate ([bmim]BF4) or 1-butyl-3-methylimidazolium hexafluorophosphate ([bmim]PF6) ionic liquids under mild and neutral conditi

Stereoselective Syntheses of Highly Functionalized Imidazolidines and Oxazolidines via Ring-Opening Cyclization of Activated Aziridines and Epoxides with Amines and Aldehydes

A mild one-pot stereospecific synthetic route to highly functionalized imidazolidines and oxazolidines via SN2-type ring-opening of the corresponding activated aziridines and epoxides with amines followed by p-toluenesulfonic acid (PTSA)-catalyzed intramolecular cyclization with aldehydes has been developed. The methodology tolerates a variety of functional groups and furnishes the desired products in high yields (up to 92%) with excellent stereoselectivities (de, ee > 99%). Interestingly, imidazolidines were formed as the cis-isomers, whereas oxazolidines were produced as trans-isomers exclusively.

Regioselective ring-opening of aziridines and epoxides with amines under catalyst- and solvent-free condition on solid phase

Ring opening of aziridines and epoxides with various amines afforded high regioselective products in high yields by solid phase reaction under catalyst- and solvent- free condition. The ring opening reaction proceeded rapidly by grinding.