105174-43-4

Basic information

• Product Name: 4-Brom-3',4'-dihydroxybutyrophenon
• CAS NO: 105174-43-4
• Molecular Weight: 259.1
• Mol File: 105174-43-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-Brom-3',4'-dihydroxybutyrophenon(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Brom-3',4'-dihydroxybutyrophenon(105174-43-4)
• EPA Substance Registry System: 4-Brom-3',4'-dihydroxybutyrophenon(105174-43-4)

Safety Data

• Hazardous Substances Data: 105174-43-4(Hazardous Substances Data)

Upstream product

• 56489-06-6 4-bromobutyryl bromide 
• 120-80-9 benzene-1,2-diol 

Relevant articles and documents

Synthesis of Phenolic Ketones, an Ester Ketone of Guaiacol, and a Ketone of Veratrole Containing Chlorine, Bromine, or Iodine in the Side-chain

The ω-bromo and ω-chloro ketones 1-8, 10-14 of phenols as well as the ω-bromo ketone 9 of veratrole are synthesized according to the Friedel-Crafts acylation (FCA) using different variations and specific reaction conditions.Under these conditions hydroquinone furnishes the esters of the ω-bromo- and ω-chlorocarboxylic acids 28-31, whereas phloroglucinol does not result in defined reaction products.Guaiacol yields 16 with an ester as well as a ketone group at its aromatic nucleus.Bromination of 3',4'-dihydroxyisobutyrophenone with CuBr2 leads to 2-bromo-3',4'-dihydroxyisobutyrophenone (15).The ω-iodo ketones 17-27 of phenols and their methyl ethers have been obtained from the corresponding ω-bromo or ω-chloro ketone on treatment with NaI in acetone.