1052114-81-4 Usage
General Description
5-(4-fluorophenyl)-4-oxo-1,4-dihydropyridine-3-carboxylic acid is a chemical compound with a molecular formula C13H9NO4F. It belongs to the class of dihydropyridines, which are widely used as calcium channel blockers in the treatment of hypertension and angina. This particular compound has a 4-fluorophenyl group attached to the 5-position of the dihydropyridine ring, and a carboxylic acid group at the 3-position. It is a key intermediate in the synthesis of various pharmaceutical compounds and may also have potential biological activities. Its structural features make it a valuable synthetic building block for the development of new drugs and materials.
Check Digit Verification of cas no
The CAS Registry Mumber 1052114-81-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,5,2,1,1 and 4 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1052114-81:
(9*1)+(8*0)+(7*5)+(6*2)+(5*1)+(4*1)+(3*4)+(2*8)+(1*1)=94
94 % 10 = 4
So 1052114-81-4 is a valid CAS Registry Number.
1052114-81-4Relevant articles and documents
QUINOLINE COMPOUNDS AS INHIBITORS OF TAM AND MET KINASES
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Paragraph 001134-001137, (2020/07/21)
Provided herein are compounds of the Formula (I) or pharmaceutically acceptable salts thereof, wherein X1, X2, X3, R1, R2, R3, R4, R5, R6 and R7 are as defined herein, which are inhibitors of one or more TAM kinases and/or c-Met kinase, and are useful in the treatment and prevention of diseases which can be treated with a TAM kinase inhibitor and/or a c-Met kinase inhibitor.
NOVEL FUSED PYRIDINE DERIVATIVES USEFUL AS c-MET TYROSINE KINASE INHIBITORS
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, (2014/01/17)
This invention relates to novel fused quinazoline derivatives of Formula I as c-Met inhibitors, their synthesis and uses for treating c-Met mediated disorders.
4-PYRIDINONE COMPOUNDS AND THEIR USE FOR CANCER
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Page/Page column 28; 35-36, (2009/09/05)
Disclosed are compounds of Formula (I)and salts thereof. Also, disclosed are methods of using the compounds in the treatment of proliferative diseases, such as cancer, and to pharmaceutical compositions comprising at least one compound of Formula (I) or a