1052175-54-8

Basic information

• Product Name: bromo(3-bromophenyl)acetonitrile
• Synonyms: bromo(3-bromophenyl)acetonitrile
• CAS NO: 1052175-54-8
• Molecular Weight: 274.942
• Mol File: 1052175-54-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: bromo(3-bromophenyl)acetonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: bromo(3-bromophenyl)acetonitrile(1052175-54-8)
• EPA Substance Registry System: bromo(3-bromophenyl)acetonitrile(1052175-54-8)

Safety Data

• Hazardous Substances Data: 1052175-54-8(Hazardous Substances Data)

Upstream product

• 31938-07-5 (3-bromophenyl)acetonitrile 

Downstream Products

• 24999-51-7 m-bromobenzoyl cyanide 
• 324008-31-3 2-(2-{2-[(3-bromo-phenyl)-phenyl-methyl]-thiazol-4-yl}-ethyl)-isoindole-1,3-dione 
• 324008-26-6 2-(3-bromo-phenyl)-2-phenyl-thioacetamide 

Relevant articles and documents

Histamine H1 receptor ligands - Part II. Synthesis and in vitro pharmacology of 2-[2-(phenylamino)thiazol-4-yl]ethanamine and 2-(2-benzhydrylthiazol-4-yl)ethanamine derivatives

New 2-[2-(phenylamino)thiazol-4-yl]ethanamine and 2-(2-benzhydrylthiazol-4-yl)ethanamine derivatives were prepared and tested in vitro as H1 receptor antagonists. The compounds with 2-phenylamino substitution with meta-halide substituents at the phenyl ring, showed weak H1-antagonistic activity (pA2: 4.62-5.04) and this activity was completely lost in the case of meta-methyl substituent (pA2 : 4). When the phenylamino group was replaced by benzhydryl groups of classic antihistamines, the resulting compounds exhibited slightly improved H1-antagonistic activity (at the meta-position pA2: 6.38-6.15; at the para-position pA2: 6.04-5.87).