10524-56-8

Basic information

• Product Name: 1-bromo-2-nitroethane
• Synonyms: 1-bromo-2-nitroethane
• CAS NO: 10524-56-8
• Molecular Weight: 153.963
• Mol File: 10524-56-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-bromo-2-nitroethane(CAS DataBase Reference)
• NIST Chemistry Reference: 1-bromo-2-nitroethane(10524-56-8)
• EPA Substance Registry System: 1-bromo-2-nitroethane(10524-56-8)

Safety Data

• Hazardous Substances Data: 10524-56-8(Hazardous Substances Data)

Usage

Physical state

Colorless to pale yellow liquid

Uses

a. Intermediate in the synthesis of pharmaceuticals and agrochemicals
b. Solvent in various chemical reactions
c. Reagent in organic synthesis

Chemical properties

a. Ability to undergo nucleophilic substitution reactions

Safety precautions

a. Toxic if ingested
b. Potentially harmful if inhaled or in contact with skin
c. Proper handling and safety measures necessary when working with this chemical

Upstream product

• 79-24-3 Nitroethane 
• 540-51-2 2-bromoethanol 
• 625-48-9 2-nitro-1-ethanol 

Downstream Products

• 15473-28-6 1,1,1,3-Tetranitro-propan 

Relevant articles and documents

Nitrate NO donor type hematoporphyrin derivative and preparation method and application thereof

The invention relates to the field of medicinal chemistry, in particular to preparation of nitrate NO donor type hematoporphyrin derivatives and application of the nitrate NO donor type hematoporphyrin derivatives in preparation of antitumor drugs. According to the invention, hematoporphyrin is used as a lead compound, nitrate capable of generating NO is selected as an NO donor by utilizing a splicing principle, and is connected to hydroxyl and carboxyl of a molecular structure through a connecting group, the nitrate NO donor type hematoporphyrin derivatives are designed and synthesized, and have a wide application prospect in the field of antitumor drugs.

Catalytic Bromination of Alkyl sp3C-H Bonds with KBr/Air under Visible Light

Alkyl sp3C-H bonds of cycloalkanes and functional branch/linear alkanes have been successfully brominated with KBr using air or O2 as an oxidant at room temperature to 40 °C. The reactions are carried out in the presence of catalytic NaNO2 in 37% HCl (aq)/solvent under visible light, combining aerobic oxidations and photochemical radical processes. For various alkane substrates, CF3CH2OH, CHCl3, or CH2Cl2 is employed as an organic solvent, respectively, to enhance the efficiency of bromination.