1052719-58-0

Basic information

• Product Name: 7-nitro-9-phenyl-3-(trifluoromethyl)-3,4-dihydroacridin-1(2H)-one
• Synonyms: 7-nitro-9-phenyl-3-(trifluoromethyl)-3,4-dihydroacridin-1(2H)-one
• CAS NO: 1052719-58-0
• Molecular Weight: 386.33
• Mol File: 1052719-58-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 7-nitro-9-phenyl-3-(trifluoromethyl)-3,4-dihydroacridin-1(2H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 7-nitro-9-phenyl-3-(trifluoromethyl)-3,4-dihydroacridin-1(2H)-one(1052719-58-0)
• EPA Substance Registry System: 7-nitro-9-phenyl-3-(trifluoromethyl)-3,4-dihydroacridin-1(2H)-one(1052719-58-0)

Safety Data

• Hazardous Substances Data: 1052719-58-0(Hazardous Substances Data)

Upstream product

• 124612-15-3 5-(trifluoromethyl)-cyclohexane-1,3-dione 
• 1775-95-7 2-amino-5-nitrobenzophenone 

Relevant articles and documents

Novel fluorinated acridone derivatives. Part 1: Synthesis and evaluation as potential anticancer agents

We report on the synthesis of a novel series of fluorinated acridones from 5-trifluoromethyl-1,3-cyclohexanedione. The cytotoxic activities of the compounds were studied in several cancer cells. Compounds 9a, 9c, 9e, 9f, and 9h exhibited significant anticancer activities in selected cell lines. Compound 9c is the most active showing GI50 that ranged in values from 0.13 to 26 μM, covering a wide range of cancer cell lines.