105285-08-3

Basic information

• Product Name: 2',6',4-trihydroxychalcone
• Synonyms: 2',6',4-trihydroxychalcone
• CAS NO: 105285-08-3
• Molecular Weight: 256.258
• Mol File: 105285-08-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2',6',4-trihydroxychalcone(CAS DataBase Reference)
• NIST Chemistry Reference: 2',6',4-trihydroxychalcone(105285-08-3)
• EPA Substance Registry System: 2',6',4-trihydroxychalcone(105285-08-3)

Safety Data

• Hazardous Substances Data: 105285-08-3(Hazardous Substances Data)

Upstream product

• 123-08-0 4-hydroxy-benzaldehyde 
• 74189-56-3 4-(tetrahydropyran-2-yloxy)benzaldehyde 
• 699-83-2 2,6-dihydroxylacetophenone 
• 110-87-2 3,4-dihydro-2H-pyran 
• 101946-89-8 4,2',6'-tris(methoxymethoxy)chalcone 
• 63854-17-1 2-hydroxy-6-[(tetrahydro-2H-pyran-2-yl)oxy]acetophenone 

Downstream Products

• 854245-26-4 4',5-diacetoxyflavan-4-one 
• 745-39-1 5,4'-diacetoxyflavanone 
• 86788-62-7 (Z)-4-methoxy-2-(4-methoxybenzylidene)benzofuran-3(2H)-one 
• 6665-67-4 5,4'-dihydroxyflavone 
• 105285-09-4 (E)-1-(2-hydroxy-6-methoxyphenyl)-3-(4-methoxyphenyl)prop-2-en-1-one 
• 86788-60-5 5,4'-dihydroxyflavanol 
• 64687-96-3 5-hydroxy-2-(4-hydroxphenyl)chroman-4-one 

Relevant articles and documents

Acid catalyzed stereoselective rearrangement and dimerization of flavenes: synthesis of dependensin

Appropriately substituted flavenes undergo stereoselective rearrangement and dimerization when treated with methanolic hydrochloric acid to give benzopyranobenzopyrans. A rationale for the rearrangement is proposed. This synthetic methodology has been used for a high yield synthesis of the natural product dependensin.

HETEROCYCLES. XIX. REACTION OF 2'-HYDROXYCHALCONES WITH ALKALINE HYDROGEN PEROXIDE

Reaction of 2'-hydroxychalcones, which contain the hydroxyl and/or the methoxyl group at the 4- and 6'-positions, with alkaline hydrogen peroxide has been examined.It is observed that these substituents intricately influence the formation of the products.

Process for treating inflammation

A process for treating inflammation locally or topically by administering a compound of the formula: STR1 wherein M and M' are hydrogen, hydroxy, halogen, lower alkyl of from 1 to 3 carbon atoms, lower alkoxy of from 1 to 3 carbon atoms; NH2, R