105310-47-2 Usage
General Description
(E)-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride is a chemical compound that consists of a cyclopropane ring with an attached carboxamide group and an aminomethyl and diethyl groups. (E)-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride is often used in research and development of pharmaceuticals and is known for its potential as an analgesic or pain-relieving agent. The hydrochloride form of this compound is commonly used to improve solubility and stability, making it easier to work with in laboratory settings. Due to its unique structure and potential therapeutic applications, (E)-2-(Aminomethyl)-N,N-diethyl-1-phenylcyclopropanecarboxamide hydrochloride is of interest in the field of medicinal chemistry and drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 105310-47-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,3,1 and 0 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 105310-47:
(8*1)+(7*0)+(6*5)+(5*3)+(4*1)+(3*0)+(2*4)+(1*7)=72
72 % 10 = 2
So 105310-47-2 is a valid CAS Registry Number.
InChI:InChI=1/C15H22N2O.ClH/c1-3-17(4-2)14(18)15(10-13(15)11-16)12-8-6-5-7-9-12;/h5-9,13H,3-4,10-11,16H2,1-2H3;1H/t13-,15-;/m0./s1
105310-47-2Relevant articles and documents
A new approach towards 1-phenyl and 1-benzyl substituted 2-(aminomethyl)cyclopropanecarboxamides as novel derivatives of the antidepressant Milnacipran
Vervisch, Karel,D'Hooghe, Matthias,Toernroos, Karl W.,De Kimpe, Norbert
experimental part, p. 3271 - 3279 (2009/10/24)
2-(2-Cyano-2-phenylethyl)aziridines were converted into novel trans-2-aminomethyl-1-phenylcyclopropanecarboxamides via regiospecific ring opening and 3-exo-tet cyclisation, thus providing the first convenient entry into the trans-isomer of Milnacipran as a useful template for further derivatisation. Furthermore, unprecedented 2-aminomethyl-1- benzylcyclopropanecarboxamides have been synthesized using two different routes starting from 2-(2-cyanoethyl)aziridines, both involving α-benzylation with respect to the nitrile group and aziridine to cyclopropane ring transformation. The Royal Society of Chemistry 2009.
