105405-52-5

Basic information

• Product Name: 3-Butyn-2-ol, 4,4',4''-(1,3,5-benzenetriyl)tris[2-methyl-
• CAS NO: 105405-52-5
• Molecular Formula: C21H24O3
• Molecular Weight: 324.42
• Mol File: 105405-52-5.mol
• Article Data: 12

Chemical Properties

• CAS DataBase Reference: 3-Butyn-2-ol, 4,4',4''-(1,3,5-benzenetriyl)tris[2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Butyn-2-ol, 4,4',4''-(1,3,5-benzenetriyl)tris[2-methyl-(105405-52-5)
• EPA Substance Registry System: 3-Butyn-2-ol, 4,4',4''-(1,3,5-benzenetriyl)tris[2-methyl-(105405-52-5)

Safety Data

• Hazardous Substances Data: 105405-52-5(Hazardous Substances Data)

Upstream product

• 626-44-8 1,3,5-Triiodobenzene 
• 115-19-5 2-methyl-but-3-yn-2-ol 
• 626-39-1 1,3,5-trisbromobenzene 

Downstream Products

• 211739-82-1 1,3,5-tris[(4'-ethynylphenyl)ethynyl]benzene 
• 220870-30-4 1,3,5-tris[4-{{(trimethylsilyl)ethynyl}phenyl}ethynyl]benzene 
• 1442466-99-0 C₃₈H₂₆Si 
• 1428643-51-9 1,3,5-tris((5-((trimethylsilyl)ethynyl)thiophen-2-yl)-ethynyl)benzene 
• 168289-78-9 1,3,5-tris(4-pyridylethynyl)benzene 
• 7567-63-7 1,3,5-Triethynylbenzene 
• 1431230-88-4 3,3',3''-(1,3,5-phenylene)tripropiolic acid 

Relevant articles and documents

Convenient preparation of di- and tri-ethynylbenzenes by cleavage of 2-hydroxy-2-methylbut-3-yn-4-yl-benzenes with water miscible reagents

2-Hydroxy-2-methylbut-3-yn-4-yl-benzenes, readily available from bromobenzenes, are efficiently cleaved by the water-miscible reagents sodium 2-propoxide in 2-propanol, or potassium hydroxide in dioxan, which facilitatese isolation of volatile ethynylbenzenes.

Direct Enzymatic Branch-End Extension of Glycocluster-Presented Glycans: An Effective Strategy for Programming Glycan Bioactivity

The sequence of a glycan and its topology of presentation team up to determine the specificity and selectivity of recognition by saccharide receptors (lectins). Structure–activity analysis would be furthered if the glycan part of a glycocluster could be efficiently elaborated in situ while keeping all other parameters constant. By using a bacterial α2,6-sialyltransferase and a small library of bi- to tetravalent glycoclusters, we illustrate the complete conversion of scaffold-presented lactoside units into two different sialylated ligands based on N-acetyl/glycolyl-neuraminic acid incorporation. We assess the ensuing effect on their bioactivity for a plant toxin, and present an analysis of the noncovalent substrate binding contacts that the added sialic acid moiety makes to the lectin. Enzymatic diversification of a scaffold-presented glycan can thus be brought to completion in situ, offering a versatile perspective for rational glycocluster engineering.

Novel planar and star-shaped molecules: Synthesis, electrochemical and photophysical properties

Three novel planar and star-shaped molecules containing thiophene-functionalized group and acetylenic spacers, 4-((5″-iodo-[2, 2′:5′,2″-terthiophen]-5-yl)ethynyl)aniline (I3TEA), 4,4′-([2,2′:5′,2″-terthiophene]-5,5″- diylbis(ethyne-2,1-diyl))dianiline (3T