10544-05-5

Basic information

• Product Name: 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-7-hydroxy-5-methoxy-
• CAS NO: 10544-05-5
• Molecular Formula: C18H16O6
• Molecular Weight: 328.321
• Mol File: 10544-05-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-7-hydroxy-5-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-7-hydroxy-5-methoxy-(10544-05-5)
• EPA Substance Registry System: 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-7-hydroxy-5-methoxy-(10544-05-5)

Safety Data

• Hazardous Substances Data: 10544-05-5(Hazardous Substances Data)

Usage

General Description

The chemical 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-7-hydroxy-5-methoxy- is a flavonoid compound with a molecular structure resembling a benzopyran ring. It contains a hydroxyl group at the 7th position and two methoxy groups at the 3rd and 5th positions of the phenyl ring. 4H-1-Benzopyran-4-one, 2-(3,4-dimethoxyphenyl)-7-hydroxy-5-methoxy- is known for its antioxidant and anti-inflammatory properties, and it has been studied for its potential therapeutic effects in various medical conditions. It is commonly found in medicinal plants and natural products, and it is being researched for its potential applications in the pharmaceutical and nutraceutical industries.

Upstream product

• 2174-64-3 5-methoxyresorcinol 
• 4687-37-0 ethyl 3,4-dimethoxybenzoylacetate 
• 62346-14-9 7,4′-dihydroxy-5,3′-dimethoxyflavone 
• 77-78-1 dimethyl sulfate 
• 520-27-4 diosmin 
• 742077-30-1 7-benzyloxy-2-(3,4-dimethoxy-phenyl)-5-hydroxy-chromen-4-one 
• 4712-12-3 5,7-dihydroxy-3',4'-dimethoxy flavone 
• 33554-52-8 3′-hydroxy-5,7,4′-trimethoxyflavone 
• 24824-54-2 3,4-dimethoxybenzoic anhydride 
• 72629-61-9 Luteolin-5,4'-dimethylether 
• 203191-62-2 7-benzyloxy-2-(3,4-dimethoxy-phenyl)-5-methoxy-chromen-4-one 

Downstream Products

• 2174-59-6 5-hydroxy-6,7,8,3',4'-pentamethoxyflavone 
• 35154-55-3 3-hydroxy-5,6,7,8,3′,4′-hexamethoxyflavone 
• 1178-24-1 3,3',4',5,6,7,8-heptamethoxyflavone 
• 1176-88-1 5-hydroxy-3,6,7,8,3',4'-hexamethoxyflavone 
• 1092093-65-6 7-{(hydrophosphoryl)-methyloxy}-3',4',5-trimethoxyflavone 
• 1092093-75-8 7-{(diisopropylphosphoryl)-methyloxy}-3',4',5-trimethoxyflavone 
• 203191-36-0 7-hydroxyethyloxy-3',4',5-trimethoxy flavone 
• 491-70-3 2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on 
• 62346-14-9 7,4′-dihydroxy-5,3′-dimethoxyflavone 
• 72629-61-9 Luteolin-5,4'-dimethylether 
• 4712-12-3 5,7-dihydroxy-3',4'-dimethoxy flavone 
• 29080-58-8 5-hydroxy-3',4',7-trimethoxyflavone 
• 855-97-0 2-(3,4-dimethoxyphenyl)-5,7-dimethoxy-4H-chromen-4-one 
• 94550-33-1 7-acetoxy-2-(3,4-dimethoxy-phenyl)-5-methoxy-chromen-4-one 

Relevant articles and documents

Synthesis of Citrus polymethoxyflavonoids and their antiproliferative activities on Hela cells

Abstract: A series of polymethoxyflavonoids (3–16) were synthesized through dehydrogenation, O-methylation, glycoside hydrolysis, bromination, microwave-assisted aromatic nucleophilic substitution, dimethyldioxirane oxidation and regioselective demethylation, starting from abundant and inexpensive natural sources naringin and hesperidin. All the synthetic compounds were test for antiproliferative activities on human cervical carcinoma Hela cell line by the standard CCK-8 assay, the result showed that most of the target compounds exhibited moderate to potent antiproliferative activities on Hela cells comparable with the positive control cis-Platin. Among them, 5-hydroxypolymethoxy flavonoid 13 showed the strongest activity (IC50 0.791 μM). Graphical Abstract: [InlineMediaObject not available: see fulltext.].

USE OF FLAVONE AND FLAVANONE DERIVATIVES IN PREPARATION OF SEDATIVE AND HYPNOTIC DRUGS

Disclosed is a use of flavones derivatives and flavanone derivatives in preparation of sedative and hypnotic drugs.

On a Thermal Transmethylation Reaction with Flavon-5-methylethers

Upon heating to 300 deg C partial luteolinemethylethers undergo transmethylation.A reaction mechanism is put foreward. - Key words: Flavonemethylethers, Thermal Transmethylation, TLC, HPLC, Reaction Mechanism