1055312-00-9Relevant articles and documents
Inhibitors of the kinase IspE: Structure-activity relationships and co-crystal structure analysis
Hirsch, Anna K. H.,Alphey, Magnus S.,Lauw, Susan,Seet, Michael,Barandun, Luzi,Eisenreich, Wolfgang,Rohdich, Felix,Hunter, William N.,Bacher, Adelbert,Diederich, Francois
supporting information; experimental part, p. 2719 - 2730 (2009/02/02)
Enzymes of the non-mevalonate pathway for isoprenoid biosynthesis are therapeutic targets for the treatment of important infectious diseases. Whereas this pathway is absent in humans, it is used by plants, many eubacteria and apicomplexan protozoa, includ