1055361-96-0

Basic information

• Product Name: bisMPA dendron
• Synonyms: Polyester bis-MPA dendron, 4 hydroxyl, 1 acetylene
• CAS NO: 1055361-96-0
• Molecular Formula: C₁₈H₂₈O₁₀
• Molecular Weight: 404.41
• Mol File: 1055361-96-0.mol
• Article Data: 7

Chemical Properties

• Melting Point: 101-105°C
• Boiling Point: 569.3±45.0 °C(Predicted)
• Appearance: /
• Density: 1.304±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 13.12±0.10(Predicted)
• CAS DataBase Reference: bisMPA dendron(CAS DataBase Reference)
• NIST Chemistry Reference: bisMPA dendron(1055361-96-0)
• EPA Substance Registry System: bisMPA dendron(1055361-96-0)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 1055361-96-0(Hazardous Substances Data)

Usage

Description

BisMPA dendron, with a calculated molecular weight of 404.4, is a type of dendron that possesses unique structural and functional properties. It is characterized by its ability to form multiple branches, which can be further functionalized with various molecules, making it a versatile building block for a wide range of applications.

Uses

Used in Chemical Synthesis:
BisMPA dendron is used as a synthetic building block for the creation of complex molecular structures. Its multiple branches allow for the attachment of various functional groups, making it a valuable tool in the synthesis of advanced materials and compounds.
Used in Drug Delivery Systems:
In the pharmaceutical industry, bisMPA dendron is used as a component in drug delivery systems. Its ability to couple with various functional molecules, such as carbohydrates, fluorescent dyes, and polymers, enables the development of targeted drug delivery systems with enhanced bioavailability and therapeutic efficacy.
Used in Diagnostics and Imaging:
BisMPA dendron is used as a component in diagnostic and imaging applications. Its compatibility with fluorescent dyes and other imaging agents allows for the development of highly sensitive and specific detection systems for various medical conditions.
Used in Material Science:
In the field of material science, bisMPA dendron is used as a building block for the development of advanced materials with unique properties. Its ability to form complex structures and couple with various functional molecules makes it a promising candidate for the creation of novel materials with tailored properties for specific applications.
Used in Nanotechnology:
BisMPA dendron is used as a component in the development of nanoscale devices and systems. Its ability to form multiple branches and couple with various functional molecules makes it a valuable tool for the creation of nanoscale structures with specific properties and functions.

Upstream product

• 919988-17-3 2-methyl-2-((prop-2-yn-1-yloxy)carbonyl)propane-1,3-diyl bis(2,2,5-trimethyl-1,3-dioxane-5-carboxylate) 
• 873849-85-5 prop-2-yn-1-yl 3-hydroxy-2-(hydroxymethyl)-2-methylpropanoate 
• 919988-15-1 propargyl 2,2,5-trimethyl-1,3-dioxane-5-carboxylate 
• 16837-14-2 2,2,5-trimethyl-1,3-dioxane-5-carboxylic acid 
• 4767-03-7 2,2-bis(hydroxymethyl)propionic acid 
• 408322-03-2 2,2,5-trimethyl-1,3-dioxane-5-carboxylic anhydride 
• 205878-78-0 isopropylidene-[G-2]-COOH 

Downstream Products

• 1351959-64-2 C₄₆H₄₀N₄O₂₆ 

Relevant articles and documents

Convergent synthesis of glycodendropeptides by click chemistry approaches

Mannosylation facilitates the uptake of immunogenic peptides by antigen-processing cells expressing mannose receptors at their surface. Mannose-receptor interactions not only induce internalization but also trigger strong T-cell stimulation, such as that of the dendritic cell-specific intercellular ICAM-3 grabbing non-integrin (DC-SIGN), a lectin that plays a key role in the immune response against different pathogens. We describe here two efficient synthetic strategies for structurally well-defined mannose-displaying glycodendropeptides with up to 16 peptide and 9 mannose copies. Our approaches integrate previously optimized synthetic methods for producing both peptide and glycan dendrimers, and make extensive use of CuI-catalyzed Huisgen 1,3-dipolar cycloaddition for both the building of the glycodendron moieties and their subsequent conjugation to the peptide components. These strategies are versatile and straightforward enabling full control of chemical structure as well as readily tunable valency. Mannose-displaying glycodendropeptides with up to 16 peptide and 9 mannose copies have been synthesized making extensive use of CuI-catalyzed Huisgen 1,3-dipolar cycloaddition for both the building of the glycodendrons and their subsequent conjugation to single peptides or peptide dendrimers based on a branched lysine scaffold. Copyright

Self-Assembly of Amphiphilic Janus Dendrimers into Mechanically Robust Supramolecular Hydrogels for Sustained Drug Release

Compounds that can gelate aqueous solutions offer an intriguing toolbox to create functional hydrogel materials for biomedical applications. Amphiphilic Janus dendrimers with low molecular weights can readily form self-assembled fibers at very low mass pr

Multivalent, bifunctional dendrimers prepared by click chemistry

Unsymmetrical dendrimers, containing both mannose binding units and coumarin fluorescent units, have been prepared using click chemistry and shown to be highly efficient, dual-purpose recognition/detection agents for the inhibition of hemagglutination. The Royal Society of Chemistry 2005.