10557-17-2 Usage
Description
1-(3-Chlorophenyl)-1,2-propanedione, also known as Bupropion USP Related Compound E, is a metabolite of Bupropion (B689625). It is characterized by its clear yellow oil appearance and is derived from the metabolism of the parent compound, Bupropion.
Uses
Used in Pharmaceutical Industry:
1-(3-Chlorophenyl)-1,2-propanedione is used as a metabolite in the pharmaceutical industry for its role in the metabolism of Bupropion (B689625). As a metabolite, it contributes to the overall pharmacological effects and safety profile of the parent drug, Bupropion, which is commonly used for the treatment of depression and as an aid to smoking cessation.
Additionally, understanding the properties and behavior of this metabolite can help researchers and pharmaceutical companies optimize the drug's formulation, dosage, and administration, potentially leading to improved therapeutic outcomes and reduced side effects for patients.
Check Digit Verification of cas no
The CAS Registry Mumber 10557-17-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,0,5,5 and 7 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 10557-17:
(7*1)+(6*0)+(5*5)+(4*5)+(3*7)+(2*1)+(1*7)=82
82 % 10 = 2
So 10557-17-2 is a valid CAS Registry Number.
10557-17-2Relevant articles and documents
New synthetic strategy for high-enantiopurity N-protected α-amino ketones and their derivatives by asymmetric hydrogenation
Sun, Tian,Hou, Guohua,Ma, Miaofeng,Zhang, Xumu
supporting information; experimental part, p. 253 - 256 (2011/04/16)
Asymmetric hydrogenation of α-dehydroamino ketones catalyzed by a rhodium-chiral phosphorus ligand complex (up to 99% ee, 1000 TON), represents an efficient approach to chiral α-amino ketones. The reduction of α-amino ketones catalyzed by palladium on carbon (Pd/C) leads to amphetamine precursors with quantitative yield and no significant enantioselectivity loss.
Palladium-catalyzed carbonation-diketonization of terminal aromatic alkenes via carbon-nitrogen bond cleavage for the synthesis of 1,2-diketones
Wang, Azhong,Jiang, Huanfeng,Li, Xianwei
supporting information; experimental part, p. 6958 - 6961 (2011/10/02)
A palladium-catalyzed carbonation-diketonization reaction of terminal alkenes via carbon-nitrogen bond cleavage under an atmosphere of oxygen has been developed. A series of 1,2-diketones were readily prepared from the reaction of aromatic terminal alkenes with nitroalkanes.
