10558-25-5

Basic information

• Product Name: 4-Bromo-3,5-dimethylisoxazole
• Synonyms: BUTTPARK 33\06-98;4-BROMO-3,5-DIMETHYLISOXAZOLE;4-BROMO-3,5-DIMETHYLISOXAZOLE 97%;4-Bromo-3,5-dimethylisoxazole, tech.;4-Bromo-3,5-dimethylisoxazole,97%;4-Bromo-3,5-dimethylisoxa...;Isoxazole, 4-broMo-3,5-diMethyl-;4-Bromo-dimethylisoxazole
• CAS NO: 10558-25-5
• Molecular Formula: C₅H₆BrNO
• Molecular Weight: 176.01
• EINECS: -0
• Product Categories: blocks;Bromides;Oxazoles;Oxazole&Isoxazole;Halogenated Heterocycles;Heterocyclic Building Blocks;Isoxazoles;IsoxazolesBuilding Blocks
• Mol File: 10558-25-5.mol
• Article Data: 2

Chemical Properties

• Melting Point: 176 °C(lit.)
• Boiling Point: 176 °C(lit.)
• Flash Point: >230 °F
• Appearance: clear colorless to light yellow liquid
• Density: 1.478 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.219mmHg at 25°C
• Refractive Index: n20/D 1.486(lit.)
• Storage Temp.: Keep Cold
• PKA: -2.35±0.28(Predicted)
• Sensitive: Light Sensitive
• BRN: 108522
• CAS DataBase Reference: 4-Bromo-3,5-dimethylisoxazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Bromo-3,5-dimethylisoxazole(10558-25-5)
• EPA Substance Registry System: 4-Bromo-3,5-dimethylisoxazole(10558-25-5)

Safety Data

• Safety Statements: 24/25
• WGK Germany: 3
• Hazardous Substances Data: 10558-25-5(Hazardous Substances Data)

Usage

Description

4-Bromo-3,5-dimethylisoxazole, also known as 3,5-dimethyl-4-bromoisoxazole, is a chemical compound characterized by its clear colorless to light yellow liquid appearance. It is a derivative of isoxazole with bromine and methyl groups attached to specific positions on the molecule, which may influence its chemical reactivity and potential applications.

Uses

Used in Chemical Synthesis:
4-Bromo-3,5-dimethylisoxazole is used as a synthetic intermediate for the preparation of various organic compounds. Its unique structure allows it to be a valuable building block in the synthesis of more complex molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 4-Bromo-3,5-dimethylisoxazole is used as a key component in the synthesis of specific pharmaceuticals. Its presence in the molecular structure can contribute to the overall activity and efficacy of the final drug product.
Used in the Preparation of (tert-butyldimethylsilyl)-(3,5-dimethylisoxazol-4-yl)phenylamine:
4-Bromo-3,5-dimethylisoxazole is used as a starting material for the preparation of (tert-butyldimethylsilyl)-(3,5-dimethylisoxazol-4-yl)phenylamine, a compound that may have potential applications in various fields, such as materials science or pharmaceuticals.
Used in the Preparation of 3,3′,5,5′-tetramethyl-4,4′-diisoxazole:
Additionally, 4-Bromo-3,5-dimethylisoxazole is utilized in the synthesis of 3,3′,5,5′-tetramethyl-4,4′-diisoxazole, which could be relevant in the development of new materials or chemicals with specific properties.

InChI:InChI=1/C5H6BrNO/c1-3-5(6)4(2)8-7-3/h1-2H3

Upstream product

• 300-87-8 3,5-dimethyl-1,2-oxazole 

Downstream Products

• 4345-46-4 3,5-dimethyl-4-phenyl-isoxazole 
• 1044822-29-8 methyl 5-bromo-4,6-dimethyl-2-phenyl-2H-1,3-oxazine-2-carboxylate 
• 1195901-24-6 (tert-butyl-dimethyl-silanyl)-(3,5-dimethyl-isoxazol-4-yl)-phenyl-amine 
• 59184-12-2 4-mesityl-3,5-dimethylisoxazole 
• 1241941-37-6 (3,4-dichlorophenyl)(3,5-dimethylisoxazol-4-yl)methanol 
• 74356-30-2 3,5-dimethylisoxazole-4-carboxamide 
• 1265614-72-9 (3,5-dimethylisoxazol-4-yl)[4-(1H-1,2,4-triazol-1-yl)phenyl]methanol 
• 1296644-79-5 C₂₄H₂₂Cl₂N₄O 
• 1356599-40-0 3-{2-(3,5-dimethyl-1,2-oxazol-4-yl)-4-[(4-{[(2E,2Z)-2-(methoxyimino)-2-phenylethyl]oxy}benzyl)oxy]phenyl}propanoic acid 
• 1356600-99-1 ethyl 3-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-4-methoxyphenyl]propanoate 
• 1356601-02-9 ethyl 3-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-4-hydroxyphenyl]propanoate 
• 1356601-04-1 3-[2-(3,5-dimethyl-1,2-oxazol-4-yl)-4-hydroxyphenyl]propanoic acid 
• 16114-47-9 3,5-dimethylisoxazole-4-boronic acid 
• 1383479-46-6 C₁₇H₂₂N₂O₂ 

Relevant articles and documents

-

-

AGONISTS OF GPR40

The present invention relates to compounds that have the ability to modulate the activity of GPR40 and are there-fore useful in the treatment of GPR40 related disorders. In addition the invention relates to the compounds, methods for their preparation, pharmaceutical compositions containing the compounds and the uses of these compounds in the treatment of certain disorders related to GPR40 activity.