1055876-49-7

Basic information

• Product Name: 3,6-difluoro-1,2-bis(p-tolylthio)benzene
• Synonyms: 3,6-difluoro-1,2-bis(p-tolylthio)benzene
• CAS NO: 1055876-49-7
• Molecular Weight: 358.476
• Mol File: 1055876-49-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,6-difluoro-1,2-bis(p-tolylthio)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 3,6-difluoro-1,2-bis(p-tolylthio)benzene(1055876-49-7)
• EPA Substance Registry System: 3,6-difluoro-1,2-bis(p-tolylthio)benzene(1055876-49-7)

Safety Data

• Hazardous Substances Data: 1055876-49-7(Hazardous Substances Data)

Upstream product

• 551-62-2 1,2,3,4-tetrafluorobenzene 
• 103-19-5 di(p-tolyl) disulfide 

Relevant articles and documents

Rhodium-catalyzed substitution reaction of aryl fluorides with disulfides: P-orientation in the polyarylthiolation of polyfluorobenzenes

In the presence of a catalytic amount of RhH(PPh3)4 and 1,2-bis(diphenylphosphino)benzene, an aromatic fluoride, an organic disulfide (0.5 equiv), and triphenylphosphine (0.5 equiv) reacted in refluxing chlorobenzene to give an aryl sulfide in high yield. Since triphenylphosphine trapped fluoride atoms forming phosphine difluoride, both organothio groups of the disulfide reacted effectively, and the fluoride substituent reacted more readily than the chloride and bromide. The reaction of hexafluorobenzene and a diaryl disulfide gave 1,4-diarylthio-2,3,5,6-tetrafluorobenzene, 1,2,4,5-tetraarylthio-3,6-difluorobenzene, and hexaarylthiobenzene in a stepwise manner; pentafluorobenzene gave 1-arylthio-2,3,5,6-tetrafluorobenzene; 1,2,3,4-tetrafluorobenzene gave 1,2-diarylthio-3,6-difluorobenzene; and 1,2,4,5-tetrafluorobenzene gave 1,4-diarylthio-2-5-difluorobenzene. The polyarylthiolation reaction of polyfluorobenzenes exhibited a strong tendency to form 1,4-difluorobenzenes. Copyright