105601-75-0Relevant articles and documents
ASYMMETRIZATION OF MESO-CYCLIC KETONES USING HOMOCHIRAL ACETAL TEMPLATES
Naruse, Yuji,Yamamoto, Hisashi
, p. 6021 - 6030 (2007/10/02)
Employing the homochiral acetal template, asymmetrization of meso-substituted cyclohexanones is explored.By the use of optically-active 2,4-pentanediol as a chiral protecting group, highly diastereoselective acetal cleavage is achieved when treated with organoaluminum reagent.Dialkylaluminum amides are also effective reagents for this reaction.