105621-26-9 Usage
Description
1(4H)-Pyridinecarboxylic acid, 3-(acetyloxy)-4-(phenylmethyl)-, methyl ester, also known as methylnicotinate, is a chemical compound with vasodilatory properties. It is characterized by its ability to enhance the absorption of other drugs through the skin, making it a valuable component in the pharmaceutical industry. Methylnicotinate is also being studied for its potential anti-inflammatory and anti-cancer properties, and is considered relatively safe with low toxicity.
Uses
Used in Pharmaceutical Industry:
1(4H)-Pyridinecarboxylic acid, 3-(acetyloxy)-4-(phenylmethyl)-, methyl ester is used as a vasodilator for promoting blood flow and improving circulation. Its vasodilatory effects make it a useful component in the development of treatments for various cardiovascular conditions.
Used in Topical Creams and Ointments:
As a transdermal delivery enhancer, 1(4H)-Pyridinecarboxylic acid, 3-(acetyloxy)-4-(phenylmethyl)-, methyl ester is used to facilitate the absorption of other drugs through the skin. This application helps to increase the effectiveness of topical medications and allows for faster relief of symptoms.
Used in Anti-Inflammatory Applications:
Methylnicotinate is being studied for its potential anti-inflammatory properties, which could make it a valuable component in the development of treatments for conditions characterized by inflammation, such as arthritis or other autoimmune disorders.
Used in Anti-Cancer Applications:
Research into the anti-cancer properties of 1(4H)-Pyridinecarboxylic acid, 3-(acetyloxy)-4-(phenylmethyl)-, methyl ester is ongoing. If proven effective, it could be used as a component in the development of new cancer treatments, potentially offering a new avenue for therapy in the fight against cancer.
Used in Drug Delivery Systems:
Methylnicotinate's ability to enhance drug absorption through the skin makes it a promising candidate for use in drug delivery systems. Its incorporation into these systems could improve the bioavailability and therapeutic outcomes of various medications, particularly those administered transdermally.
Check Digit Verification of cas no
The CAS Registry Mumber 105621-26-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,6,2 and 1 respectively; the second part has 2 digits, 2 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 105621-26:
(8*1)+(7*0)+(6*5)+(5*6)+(4*2)+(3*1)+(2*2)+(1*6)=89
89 % 10 = 9
So 105621-26-9 is a valid CAS Registry Number.
105621-26-9Relevant articles and documents
Highly Regio- and Chemo-selective γ-Addition of Benzylic Group to N-Alkoxycarbonylpyridinium Salts by means of Organotin Reagent
Yamaguchi, Ryohei,Moriyasu, Masataka,Kawanisi, Mituyosi
, p. 211 - 214 (2007/10/02)
Benzyltin reagents undergo highly regio- and chemo-selective γ-addition to a variety of N-acylpyridinium salts to give 4-benzyl-1,4-dihydropyridines exclusively in good yields.