105707-24-2 Usage
General Description
2-Acetyl-3-amino-5-phenylthiophene, also known as AAPT, is a chemical compound containing a thiophene ring with an acetyl group at the 2 position and an amino group at the 3 position, as well as a phenyl group at the 5 position. It is commonly used as a building block in the synthesis of organic compounds, particularly in the pharmaceutical industry for the development of biologically active molecules. AAPT has been found to exhibit various biological activities, including anticancer, antiallergic, and antihistaminic properties. Its unique structure and diverse reactivity make it a valuable compound for the creation of new drugs and other bioactive molecules.
Check Digit Verification of cas no
The CAS Registry Mumber 105707-24-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,7,0 and 7 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 105707-24:
(8*1)+(7*0)+(6*5)+(5*7)+(4*0)+(3*7)+(2*2)+(1*4)=102
102 % 10 = 2
So 105707-24-2 is a valid CAS Registry Number.
InChI:InChI=1/C12H11NOS/c1-8(14)12-10(13)7-11(15-12)9-5-3-2-4-6-9/h2-7H,13H2,1H3
105707-24-2Relevant articles and documents
2-Bromo-2-chloro-3-arylpropanenitriles as C-3 Synthons for the Synthesis of Functionalized 3-Aminothiophenes
Batsyts, Sviatoslav,Shehedyn, Maksym,Goreshnik, Evgeny A.,Obushak, Mykola D.,Schmidt, Andreas,Ostapiuk, Yurii V.
, p. 7842 - 7856 (2019/12/24)
2-Bromo-2-chloro-3-arylpropanenitriles can be prepared by Meerwein reaction from 2-chloroacrylonitrile and various aryldiazonium salts under copper(II) bromide catalysis. They proved to be stable compounds which form 2-chlorocinnnamonitriles upon treatment with bases. Reaction of the title compounds with substituted thioglycolates gave substituted 3-aminothiophenes which have not yet been accessible by other routes. Three-component reactions with the title compound, sodium sulfide and bromonitromethane, chloroacetonitrile, or ethyl 4-chloroacetoacetate gave 2-nitro- and 2-cyano-substituted 3-aminothiophenes, and thienopyridinediones in high yields and in one single step, respectively.
