10576-04-2Relevant articles and documents
Dehydrogenation of amines to nitriles in aqueous micelles
Biondini, Daniele,Brinchi, Lucia,Germani, Raimondo,Goracci, Laura,Savelli, Gianfranco
, p. 3060 - 3063 (2005)
An aqueous reaction medium, based on a surfactant solution of dimethyldodecylamine N-oxide (DDAO) has been developed for the oxidative dehydrogenation of primary amines using NiSO4 as catalyst and K 2S2O8 as oxidant. This reaction medium enhances the rate of the reaction relative to other media previously reported in the literature, which are also toxic. The reactions of various aliphatic and cyclic amines have been investigated and gave nitriles with yields of >90% in mild conditions. The aqueous surfactant solution and reagents were recycled for future use. Wiley-VCH Verlag GmbH & Co. KGaA, 2005.
Preparation of nitrogen-doped carbon supported cobalt catalysts and its application in the reductive amination
Yuan, Ziliang,Liu, Bing,Zhou, Peng,Zhang, Zehui,Chi, Quan
, p. 347 - 356 (2019/01/24)
The use of non-noble metal catalysts with high activity is of great importance for organic transformations. Herein, nitrogen-doped carbon supported cobalt catalysts with high surface area up to 981.2 m2/g were prepared via the simple pyrolysis of cobalt coordinated organic polymers with silica as the hard template. The pyrolysis temperature showed a great effect on the structure and properties of the as-prepared catalysts. The Co@NC-800 catalyst with the pyrolysis temperature of 800 °C demonstrated a high activity for the selective reductive amination of carbonyl compounds to primary amines with ammonia and hydrogen. Structurally-diverse primary amines with yields in the range from 81.8% to 100% were attained under the optimal conditions. The Co@NC-800 catalyst could be reused without the loss of its activity. The Co@NC-800 catalyst demonstrated comparable activity as the reported heterogeneous noble metal catalysts.
A ruthenium racemisation catalyst for the synthesis of primary amines from secondary amines
Pingen, Dennis,Altinta?, ?i?dem,Rudolf Schaller, Max,Vogt, Dieter
, p. 11765 - 11771 (2016/07/28)
A Ru-based half sandwich complex used in amine and alcohol racemization reactions was found to be active in the splitting of secondary amines to primary amines using NH3. Conversions up to 80% along with very high selectivities were achieved. However, after about 80% conversion the catalyst lost activity. Similar to Shvo's catalyst, the complex might deactivate under the influence of ammonia. It was revealed that not NH3 but mainly the primary amine is responsible for the deactivation.
