1058-58-8

Basic information

• Product Name: 16-(4-methoxy-benzylidene)-5α-androstan-3β-ol-17-one
• Synonyms: 16-(4-methoxy-benzylidene)-5α-androstan-3β-ol-17-one
• CAS NO: 1058-58-8
• Molecular Weight: 408.581
• Mol File: 1058-58-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 16-(4-methoxy-benzylidene)-5α-androstan-3β-ol-17-one(CAS DataBase Reference)
• NIST Chemistry Reference: 16-(4-methoxy-benzylidene)-5α-androstan-3β-ol-17-one(1058-58-8)
• EPA Substance Registry System: 16-(4-methoxy-benzylidene)-5α-androstan-3β-ol-17-one(1058-58-8)

Safety Data

• Hazardous Substances Data: 1058-58-8(Hazardous Substances Data)

Upstream product

• 481-29-8 Epiandrosterone 
• 123-11-5 4-methoxy-benzaldehyde 
• 1239-31-2 3β-acetoxy-5α-androstan-17-one 

Downstream Products

• 875014-48-5 (16R,5'S)(8β,9α,14α)-3β-hydroxy-5α-androstano[17,16-c]-1'H-5'-(p-methoxyphenyl)pyrazoline 
• 1428382-47-1 C₄₂H₄₇NO₄S 
• 1310798-94-7 16-(4-methoxy-benzylidene)-3β-pyrrolidino-5α-androstan-17β-yl acetate 
• 1310798-93-6 16-(4-methoxy-benzylidene)-3β-piperidino-5α-androstan-17β-yl acetate 
• 1312543-10-4 16-(4-methoxy-benzylidene)-3β-(4-methylpiperazinyl)-5α-androstan-17β-ol 
• 1312543-09-1 16-(4-methoxy-benzylidene)-3β-morpholino-5α-androstan-17β-ol 
• 1312543-08-0 16-(4-methoxy-benzylidene)-3β-pyrrolidino-5α-androstan-17β-ol 
• 1312543-07-9 16-(4-methoxy-benzylidene)-3β-piperidino-5α-androstan-17β-ol 
• 1312542-83-8 16-(4-methoxy-benzylidene)-3β-(4-methylpiperazinyl)-5α-androstan-17-one 
• 1312542-82-7 16-(4-methoxy-benzylidene)-3β-morpholino-5α-androstan-17-one 
• 1312542-81-6 16-(4-methoxy-benzylidene)-3β-pyrrolidino-5α-androstan-17-one 
• 1312542-80-5 16-(4-methoxy-benzylidene)-3β-piperidino-5α-androstan-17-one 
• 1312542-74-7 16-(4-methoxy-benzylidene)-5α-androstan-3,17-dione 
• 1310798-96-9 16-(4-methoxy-benzylidene)-3β-(4-methylpiperazinyl)-5α-androstan-17β-yl acetate 

Relevant articles and documents

Synthesis of novel 16-spiro steroids: Spiro-7′-(aryl)tetrahydro-1H- pyrrolo[1,2-c][1,3]thiazolo-trans-androsterone hybrid heterocycles

The 1,3-dipolar cycloaddition of azomethine ylide derived in situ from the reaction of acenaphthylene-1,2-dione and 1,3-thiazolane-4-carboxylic acid to various exocyclic dipolarophiles synthesized from trans-androsterone and trans-dehydroandrosterone afforded a library of novel spiro[5′.2″] acenaphthylene-1″-one-spiro[16.6′]-(7′-aryl) -tetrahydro-1H-pyrrolo [1,2-c][1,3]thiazolo-trans-androsterone/ dehydroandrosterone hybrid heterocycles respectively. These reactions proceeded stereo-specifically affording a single isomer of the 16-spiro steroids in excellent yields.

Peracid Oxidation of 16-Arylidene- and 16-Alkylidene-17-oxo-steroids

Peracid oxidation of 16-arylidene- and 16-alkylidene-5α-androstan-17-ones (1) - (6) gave no α,β-unsaturated δ-lactones, but resulted mainly in products of direct oxidation of the olefinic double bond.