1058165-52-8

Basic information

• Product Name: tert-butyl 16-(2,4-dinitrophenylamino)-2-oxo-7,10,13-trioxa-3-azahexadecyloxycarbamate
• Synonyms: tert-butyl 16-(2,4-dinitrophenylamino)-2-oxo-7,10,13-trioxa-3-azahexadecyloxycarbamate
• CAS NO: 1058165-52-8
• Molecular Weight: 559.574
• Mol File: 1058165-52-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl 16-(2,4-dinitrophenylamino)-2-oxo-7,10,13-trioxa-3-azahexadecyloxycarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl 16-(2,4-dinitrophenylamino)-2-oxo-7,10,13-trioxa-3-azahexadecyloxycarbamate(1058165-52-8)
• EPA Substance Registry System: tert-butyl 16-(2,4-dinitrophenylamino)-2-oxo-7,10,13-trioxa-3-azahexadecyloxycarbamate(1058165-52-8)

Safety Data

• Hazardous Substances Data: 1058165-52-8(Hazardous Substances Data)

Upstream product

• 1058165-51-7 N-(3-(2-(2-(3-aminopropoxy)ethoxy)ethoxy)propyl)-2,4-dinitroaniline 
• 42989-85-5 [({[(2-methyl-2-propanyl)oxy]carbonyl}amino)oxy]acetic acid 

Downstream Products

• 1180486-07-0 2-(aminooxy)-N-(3-(2-(2-(3-(2,4-dinitrophenylamino)propoxy)ethoxy)ethoxy)propyl)acetamide 

Relevant articles and documents

New aldehyde tag sequences identified by screening formylglycine generating enzymes in vitro and in vivo

Formylglycine generating enzyme (FGE) performs a critical posttranslational modification of type I sulfatases, converting cysteine within the motif CxPxR to the aldehyde-bearing residue formylglycine (FGly). This concise motif can be installed within heterologous proteins as a genetically encoded aldehyde tag for site-specific labeling with aminooxy- or hydrazide-functionalized probes. In this report, we screened FGEs from M. tuberculosis and S. coelicolor against synthetic peptide libraries and identified new substrate sequences that diverge from the canonical motif. We found that E. coli-s FGE-like activity is similarly promiscuous, enabling the use of novel aldehyde tag sequences for in vivo modification of recombinant proteins. Copyright