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105836-68-8

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105836-68-8 Usage

General Description

Benzenamine, 3,5-dichloro-N-phenyl- is a chemical compound that belongs to the class of amines. It is also known by its common name, 3,5-dichloroaniline. Benzenamine, 3,5-dichloro-N-phenyl- is widely used in the production of dyes, agrochemicals, and pharmaceuticals. It is a pale yellow to brown solid with a slightly musty odor. Benzenamine, 3,5-dichloro-N-phenyl- is considered to be toxic if ingested, inhaled, or comes into contact with the skin, and can cause irritation to the eyes, skin, and respiratory system. Therefore, proper safety precautions and handling procedures should be followed when working with this chemical.

Check Digit Verification of cas no

The CAS Registry Mumber 105836-68-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,8,3 and 6 respectively; the second part has 2 digits, 6 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 105836-68:
(8*1)+(7*0)+(6*5)+(5*8)+(4*3)+(3*6)+(2*6)+(1*8)=128
128 % 10 = 8
So 105836-68-8 is a valid CAS Registry Number.

105836-68-8Relevant articles and documents

O-iodoxybenzoic acid mediated N-arylation of aromatic amines by using arylhydrazines as the arylating counterpart

Jadhav, Ravindra R.,Huddar, Sameerana N.,Akamanchi, Krishnacharya G.

, p. 6779 - 6783 (2013)

Through free-radical trapping experiments we have established, for the first time, the combination of arylhydrazines with o-iodoxybenzoic acid (IBX) for the generation of aryl free radicals. On the basis of this finding, a method was developed for the N-arylation of aromatic amines under mild conditions (base-free, -5 °C) by using arylhydrazines as the arylating counterpart and arylamines. The scope of this method was demonstrated by using a number of arylhydrazines and arylamines, which gave the N-arylated amines in good yields. Through free-radical trapping experiments, the present work describes the combination of arylhydrazines with o-iodoxybenzoic acid (IBX) for the generation aryl free radicals. This finding is exploited in the development of a mild method for the N-arylation of arylamines by using arylhydrazines as the arylating agents. The scope of this method is demonstrated through a number of examples. Copyright

N,N-diacylpiperazine tachykinin antagonists

-

, (2008/06/13)

Diacylpiperazines of general structure STR1 are tachykinin receptor antagonists useful in the treatment of inflammatory diseases, pain or migraine, and asthma, and calcium channel blockers useful in the treatment of cardiovascular conditions such as angina, hypertension or ischemia.

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