105862-10-0 Usage
Description
Cytidine, N-benzoyl-2'-deoxy-5'-O-(triphenylmethyl)is a modified nucleoside derived from cytidine, which consists of the nucleobase cytosine attached to a ribose sugar. This specific derivative features a benzoyl group attached to the 2'-deoxyribose sugar and a triphenylmethyl (trityl) protecting group on the 5'-hydroxyl group. These modifications are designed to facilitate the synthesis of oligonucleotides by protecting the 5'-hydroxyl group during coupling and deprotection processes, thereby enhancing the stability and resistance to degradation of the resulting oligonucleotides.
Uses
Used in Pharmaceutical Industry:
Cytidine, N-benzoyl-2'-deoxy-5'-O-(triphenylmethyl)is utilized as a key intermediate in the synthesis of oligonucleotides for various pharmaceutical applications. Its protective trityl group ensures that the 5'-hydroxyl group remains intact and unreacted during the assembly of the oligonucleotide chain, which is crucial for maintaining the integrity and functionality of the final product.
Used in Research and Development:
In the field of molecular biology and genetics, Cytidine, N-benzoyl-2'-deoxy-5'-O-(triphenylmethyl)serves as a valuable compound for the development of new techniques and methodologies in nucleic acid chemistry. Its protective features allow researchers to explore novel approaches to oligonucleotide synthesis and manipulation, potentially leading to advancements in gene therapy, diagnostics, and other biotechnological applications.
Used in Diagnostics:
Cytidine, N-benzoyl-2'-deoxy-5'-O-(triphenylmethyl)can be employed in the creation of modified oligonucleotide probes for diagnostic assays, such as PCR, FISH, or microarrays. The enhanced stability and resistance to degradation provided by the benzoyl and trityl modifications can improve the performance and reliability of these diagnostic tools, leading to more accurate and consistent results in medical and research settings.
Check Digit Verification of cas no
The CAS Registry Mumber 105862-10-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,8,6 and 2 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 105862-10:
(8*1)+(7*0)+(6*5)+(5*8)+(4*6)+(3*2)+(2*1)+(1*0)=110
110 % 10 = 0
So 105862-10-0 is a valid CAS Registry Number.
105862-10-0Relevant articles and documents
Modified oligodeoxyribonucleoditides
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, (2008/06/13)
Compounds for the treatment or prophylaxis of a viral infection in a mammal, which may be human, are provided. The compounds are oligodeoxyribonucleic acid derivatives, and a novel route to such compounds is also provided together with intermediates of mo
