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1058653-74-9

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1058653-74-9 Usage

Description

5-[5-(2-Chloroacetyl)-2-ethoxyphenyl]-1,6-dihydro-1-Methyl-3-propyl-7H-pyrazolo[4,3-d]pyriMidin-7-one is a complex organic compound with a unique chemical structure. It is characterized by its off-white to pale yellow solid appearance and belongs to the class of phosphodiesterase inhibitors, similar to the related compound Chlorodenafil.

Uses

Used in Pharmaceutical Industry:
5-[5-(2-Chloroacetyl)-2-ethoxyphenyl]-1,6-dihydro-1-Methyl-3-propyl-7H-pyrazolo[4,3-d]pyriMidin-7-one is used as a phosphodiesterase inhibitor for the treatment of various medical conditions. Its ability to inhibit specific phosphodiesterase enzymes can lead to increased levels of cyclic nucleotides, such as cyclic guanosine monophosphate (cGMP), which play a crucial role in regulating blood flow and smooth muscle relaxation.
Used in Research Applications:
In addition to its potential therapeutic applications, 5-[5-(2-Chloroacetyl)-2-ethoxyphenyl]-1,6-dihydro-1-Methyl-3-propyl-7H-pyrazolo[4,3-d]pyriMidin-7-one can be utilized in research settings to study the role of phosphodiesterase enzymes in various biological processes. 5-[5-(2-Chloroacetyl)-2-ethoxyphenyl]-1,6-dihydro-1-Methyl-3-propyl-7H-pyrazolo[4,3-d]pyriMidin-7-one can serve as a valuable tool for understanding the mechanisms of action and potential therapeutic targets in the development of new drugs and treatments.
Used in Drug Development:
5-[5-(2-Chloroacetyl)-2-ethoxyphenyl]-1,6-dihydro-1-Methyl-3-propyl-7H-pyrazolo[4,3-d]pyriMidin-7-one can also be employed in the development of new drugs and pharmaceutical agents. Its unique chemical structure and properties make it a promising candidate for further research and optimization to improve its efficacy, selectivity, and safety profile in treating specific medical conditions.
Overall, 5-[5-(2-Chloroacetyl)-2-ethoxyphenyl]-1,6-dihydro-1-Methyl-3-propyl-7H-pyrazolo[4,3-d]pyriMidin-7-one is a versatile compound with potential applications in various industries, particularly in the pharmaceutical and research sectors. Its unique properties and potential therapeutic effects make it an interesting subject for further investigation and development.

Check Digit Verification of cas no

The CAS Registry Mumber 1058653-74-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,5,8,6,5 and 3 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1058653-74:
(9*1)+(8*0)+(7*5)+(6*8)+(5*6)+(4*5)+(3*3)+(2*7)+(1*4)=169
169 % 10 = 9
So 1058653-74-9 is a valid CAS Registry Number.

1058653-74-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-[5-(2-chloroacetyl)-2-ethoxyphenyl]-1-methyl-3-propyl-4H-pyrazolo[4,3-d]pyrimidin-7-one

1.2 Other means of identification

Product number -
Other names Chlorodenafil

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1058653-74-9 SDS

1058653-74-9Relevant articles and documents

A synthesis method of sildenafil analogs

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Paragraph 0020; 0045; 0046, (2017/08/25)

The invention provides a synthesis method of a sildenafil analog. The chemical name of the sildenafil analog is 5-[2-ethoxy-5-(4-methylpiperazine-1-yl-thiocarbonyl)]phenyl-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazol[4,3d]pyrimidine-7-thioketone; the sildenafil analog is prepared from 5-(2-ethoxy)phenyl-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazol[4,3-d]pyrimidine-7-one as a raw material through four steps of chemical reactions. The synthesis method of the sildenafil analog is simple in synthesis step operations, economic and environmentally friendly; the yield of each step is above 75% and the total yield is relatively high; the synthesis method is suitable for industrial production.

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