1058717-64-8Relevant articles and documents
Design, synthesis of novel peptidomimetic derivatives of 4-HPR for rhabdoid tumors
Das, Bhaskar C.,Smith, Melissa E.,Kalpana, Ganjam V.
experimental part, p. 4177 - 4180 (2009/05/07)
Rhabdoid tumors (RTs) are an extremely aggressive pediatric malignancy that results from loss of the INI1/hSNF5 tumor suppressor gene. Loss of INI1 results in aberrant expression of Cyclin D1, which supports rhabdoid tumorigenesis and survival. 4-HPR, a s