105887-23-8Relevant articles and documents
Synthesis of functionalized γ-lactones via a three-component cascade reaction catalyzed by consecutive N-heterocyclic carbene systems
Zhao, Qian,Han, Bo,Wang, Biao,Leng, Hai-Jun,Peng, Cheng,Huang, Wei
, p. 26972 - 26976 (2015)
Two consecutive N-heterocyclic carbene (NHC) catalytic systems were combined in a one-pot cascade reaction for the assembly of aromatic aldehydes and 2-haloenals into a structurally complex γ-lactone backbone. To our knowledge, this is the first report of NHC-catalyzed [3 + 2] annulation of α,β-unsaturated acylazoliums with 1,2-bisnucleophiles.
Lipophilic NHC assisted one-pot synthesis of syncarpamide analogues in aqueous medium
Suresh, Pavithira,Selva Ganesan, Subramaniapillai
, p. 6257 - 6261 (2019/04/25)
Lipophilic NHC catalysis in aqueous medium was reported for the synthesis of biologically relevant (a)symmetrically substituted and unsymmetrically substituted syncarpamide analogues. All the reported reactions were performed in the absence of any expensive metal salts or additives. A diverse array of syncarpamide analogues was obtained in good yields. Lipophilic NHC catalysis was also extended to chemoselective transesterification reactions.
