105888-54-8 Usage
Description
Pyrroxamycin is a tricyclic pyrrole-containing antibiotic that was first isolated from Streptomyces fumanus Sveshnikova in the mid-1980s. It is known for its moderate insecticidal and acaricidal activity, and through systematic structural changes, novel synthetic pyrrole derivatives with increased insecticidal activity and mammalian safety have been developed. Pyrroxamycin and its synthetic congeners act as uncouplers of mitochondrial oxidative phosphorylation.
Uses
Used in Agriculture:
Pyrroxamycin is used as an insecticide and acaricide for controlling pests in various crops. Its moderate insecticidal and acaricidal activity, along with the development of novel synthetic pyrrole derivatives with increased activity and mammalian safety, make it a valuable tool in integrated pest management strategies.
Used in Pharmaceutical Industry:
Pyrroxamycin and its synthetic congeners, being uncouplers of mitochondrial oxidative phosphorylation, have potential applications in the development of new drugs targeting various diseases, including cancer and parasitic infections. Further research and development are needed to explore their therapeutic potential and optimize their safety and efficacy profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 105888-54-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,8,8 and 8 respectively; the second part has 2 digits, 5 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 105888-54:
(8*1)+(7*0)+(6*5)+(5*8)+(4*8)+(3*8)+(2*5)+(1*4)=148
148 % 10 = 8
So 105888-54-8 is a valid CAS Registry Number.
InChI:InChI=1/C12H6Cl4N2O4/c13-4-1-5-10(6(14)2-4)21-3-22-11(5)8-9(18(19)20)7(15)12(16)17-8/h1-2,11,17H,3H2/t11-/m0/s1