105900-59-2

Basic information

• Product Name: Benzenepropanoic acid, b-(acetylamino)-, methyl ester
• CAS NO: 105900-59-2
• Molecular Formula: C12H15NO3
• Molecular Weight: 221.256
• Mol File: 105900-59-2.mol
• Article Data: 36

Chemical Properties

• CAS DataBase Reference: Benzenepropanoic acid, b-(acetylamino)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoic acid, b-(acetylamino)-, methyl ester(105900-59-2)
• EPA Substance Registry System: Benzenepropanoic acid, b-(acetylamino)-, methyl ester(105900-59-2)

Safety Data

• Hazardous Substances Data: 105900-59-2(Hazardous Substances Data)

Upstream product

• 3646-50-2 3-Amino-3-phenylpropionic acid 
• 67-56-1 methanol 
• 1426822-57-2 C₁₃H₁₄F₃NO₃ 
• 108-24-7 acetic anhydride 
• 110425-60-0 N-acetyl-4-phenyl-β-propiolactam 
• 86971-60-0 (Z)-3-amino-3-phenylacrylic acid methyl ester 
• 614-27-7 methyl 3-oxo-3-phenylpropionate 
• 40638-98-0 (R/S)-3-(acetylamino)-3-phenylpropanoic acid 
• 100-52-7 benzaldehyde 
• 188488-70-2 (S)-methyl 3-(4-methoxyphenylamino)-3-phenylpropanoate 
• 98-86-2 acetophenone 
• 79229-99-5 (Z)-N-(4'-methoxyphenyl)methyl-3-amino-3-phenyl acrylate 
• 37088-66-7 (3S)-methyl 3-amino-3-phenylpropanoate 
• 75-36-5 acetyl chloride 

Downstream Products

• 67654-57-3 methyl (R)-3-acetamido-3-phenylpropanoate 
• 67654-57-3 methyl (S)-3-acetylamino-3-phenylpropionate 
• 3646-50-2 3-Amino-3-phenylpropionic acid 
• 117020-31-2 (R)-N-acetyl-3-amino-3-phenylpropionic acid 
• 136744-94-0 3-ethylamino-3-phenyl-1-propanol 

Relevant articles and documents

Rhodium-catalyzed asymmetric hydrogenation of functionalized olefins using monodentate spiro phosphoramidite ligands

Novel chiral monodentate phosphorus ligands, SIPHOS, were conveniently synthesized from 1,1′-spirobiindane-7,7′-diol. The Rh complexes of SIPHOS can catalyze the hydrogenation of α-dehydroamino esters in mild conditions, providing α-amino acid derivatives

Phosphite-thioether/selenoether Ligands from Carbohydrates: An Easily Accessible Ligand Library for the Asymmetric Hydrogenation of Functionalized and Unfunctionalized Olefins

A large family of phosphite-thioether/selenoether ligands has been easily prepared from accessible L-(+)-tartaric acid and D-(+)-mannitol and applied in the M-catalyzed (M=Ir, Rh) asymmetric hydrogenation of a broad number of substrates (46 in total). Its highly modular architecture has been crucial to maximize the catalytic performance. Improving most of the reported approaches, this ligand family presents a broad substrate scope. By selecting the ligand parameters high enantioselectivities (ee's up to 99 %) have therefore been achieved in a broad range of both, functionalized and unfunctionalized substrates. Interestingly, both enantiomers of the hydrogenation products can be usually achieved by changing the ligand parameters.

Nickel-catalyzed enantioselective hydrogenation of β-(acylamino)acrylates: Synthesis of chiral β-amino acid derivatives

The nickel-catalyzed asymmetric hydrogenation of β-(acylamino)acrylates has been developed, affording chiral β-amino acid derivatives with excellent yields (95-99% yield) and enantioselectivities (97-99% ee). With the Ni-Binapine system, high enantioselectivities (98-99% ee) have also been obtained in the hydrogenation of Z/E isomeric mixtures of β-alkyl and β-aryl β-(acylamino)acrylates. The synthesis of chiral β-amino acid derivatives on a gram scale has also been achieved with 0.2 mol % catalyst loading.

Lipases in β-dipeptide synthesis in organic solvents

A number of β-dipeptides were prepared by two-step lipase-catalyzed reactions where N-acetylated β-amino esters were first activated as 2,2,2-trifluoroethyl esters with Candida antarctica lipase B (CAL-B). The activated esters were then used to acylate a

2,3-BISPHOSPHINOPYRAZINE DERIVATIVE, METHOD FOR PRODUCING SAME, TRANSITION METAL COMPLEX, ASYMMETRIC CATALYST, AND METHOD FOR PRODUCING ORGANIC BORON COMPOUND

Provided is a 2,3-bisphosphinopyrazine derivative represented by the following general formula (1), wherein R1, R2, R3, and R4 represent an optionally substituted straight-chain or branched alkyl group having 1 to 10 carbon atoms, an optionally substituted cycloalkyl group, an optionally substituted adamantyl group, or an optionally substituted phenyl group, R5 represents an optionally substituted alkyl group having 1 to 10 carbon atoms or an optionally substituted phenyl group, each R5 may be the same group or a different group, R6 represents a monovalent substituent, n denotes an integer of 0 to

Chiral ferrocene phosphine-indole aminophosphine ligand as well as preparation method and application thereof

The invention discloses a chiral ferrocene phosphine-indole aminophosphine ligand as well as a preparation method and application thereof. The preparation method comprises the following steps: dissolving a chiral ferrocene phosphine-indole intermediate in

P-Stereogenic N-Phosphine-Phosphite Ligands for the Rh-Catalyzed Hydrogenation of Olefins

We have identified a successful family of simple P-stereogenic N-phosphine-phosphite ligands for the Rh-catalyzed asymmetric hydrogenation of olefins. These catalysts show excellent enantiocontrol for α-dehydroamino acid derivatives and α-enamides (ee's u