105986-52-5

Basic information

• Product Name: Benzenepropanoic acid, 2-(methoxycarbonyl)-, ethyl ester
• CAS NO: 105986-52-5
• Molecular Formula: C13H16O4
• Molecular Weight: 236.268
• Mol File: 105986-52-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzenepropanoic acid, 2-(methoxycarbonyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoic acid, 2-(methoxycarbonyl)-, ethyl ester(105986-52-5)
• EPA Substance Registry System: Benzenepropanoic acid, 2-(methoxycarbonyl)-, ethyl ester(105986-52-5)

Safety Data

• Hazardous Substances Data: 105986-52-5(Hazardous Substances Data)

Upstream product

• 3054-95-3 acrylaldehyde diethyl acetal 
• 610-97-9 o-iodo-methyl-benzoic acid 
• 104089-16-9 2-ethoxycarbonyethylzinc iodide 

Relevant articles and documents

3-arylpropanoate esters through the palladium-catalyzed reaction of aryl halides with acrolein diethyl acetal

The reaction of aryl halides with acrolein diethyl acetal in the presence of Pd(OAc)2, n-Bu3N, and n-Bu4NCl in DMF at 90°C affords ethyl 3-arylpropanoates. A variety of functional groups are tolerated in the aryl halides, including ether, aldehyde, ketone, ester, nitrile, and nitro groups. ortho-Substituents do not hamper the reaction. 3-Arylpropanoate esters were isolated in good to excellent yields with many neutral, electron-rich and electron-poor aryl iodides and electron-poor aryl bromide. Neutral and electron-rich aryl bromides gave the desired ester in moderate yields.