105986-53-6

Basic information

• Product Name: Benzenebutanoic acid, 2-(methoxycarbonyl)-, ethyl ester
• CAS NO: 105986-53-6
• Molecular Formula: C14H18O4
• Molecular Weight: 250.295
• Mol File: 105986-53-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Benzenebutanoic acid, 2-(methoxycarbonyl)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenebutanoic acid, 2-(methoxycarbonyl)-, ethyl ester(105986-53-6)
• EPA Substance Registry System: Benzenebutanoic acid, 2-(methoxycarbonyl)-, ethyl ester(105986-53-6)

Safety Data

• Hazardous Substances Data: 105986-53-6(Hazardous Substances Data)

Upstream product

• 610-97-9 o-iodo-methyl-benzoic acid 
• 104089-17-0 ethyl 4-(iodozincio)butanoate 
• 7425-53-8 ethyl 4-iodobutyrate 
• 693232-15-4 2-(methoxycarbonyl)phenylzinc iodide 

Relevant articles and documents

Novel Rh catalysis in cross-coupling between alkyl halides and arylzinc compounds possessing ortho-COX (X = OR, NMe2, or Ph) groups

Rh-dppf was found to be an efficient catalyst for the cross-coupling between primary alkyl halides bearings-hydrogens and arylzinc compounds possessing carbonyl groups such as ester, amide, or ketone at the ortho position. Various functional groups such as ester, nitrite, or acyloxylate moieties on the halides were tolerated under the catalysis conditions. Arylzinc compounds free of ortho-carbonyl groups reacted well with ethyl 3-iodopropanoate, suggesting that the essential intramolecular interaction between carbonyl groups and Rh promotes the reductive elimination.