10602-14-9

Basic information

• Product Name: 2-hydroxypropyl dihydrogen phosphate
• Synonyms: 2,3-hydroxy-1-propyl dihydrogen phosphate
• CAS NO: 10602-14-9
• Molecular Formula: C₃H₉O₅P
• Molecular Weight: 156.0743
• Mol File: 10602-14-9.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 348°C at 760 mmHg
• Flash Point: 164.2°C
• Density: 1.538g/cm³
• Vapor Pressure: 3.19E-06mmHg at 25°C
• Refractive Index: 1.486
• CAS DataBase Reference: 2-hydroxypropyl dihydrogen phosphate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-hydroxypropyl dihydrogen phosphate(10602-14-9)
• EPA Substance Registry System: 2-hydroxypropyl dihydrogen phosphate(10602-14-9)

Safety Data

• Hazardous Substances Data: 10602-14-9(Hazardous Substances Data)

Upstream product

• 996-21-4 1-iodopropan-2-ol 
• 75-56-9 methyloxirane 
• 7647-01-0 hydrogenchloride 
• 20636-79-7 propylene hydrogen phosphate 
• 57-55-6 propylene glycol 
• 110-86-1 pyridine 
• 10025-87-3 trichlorophosphate 
• 4281-46-3 2-hydroxypropyl-p-nitrophenyl phosphate 

Downstream Products

• 926-43-2 phosphoric acid mono-(2-oxo-propyl) ester 
• 627-69-0 2-hydroxypropyl acetate 

Relevant articles and documents

A novel method for the synthesis of acetyl phosphate

A facile method for the synthesis of acetyl phosphate by a reaction of 2-hydroxypropylphosphate with acetic acid is described. Copyright Taylor & Francis Group, LLC.

Regioselective phosphorylation of carbohydrates and various alcohols by bacterial acid phosphatases; probing the substrate specificity of the enzyme from Shigella flexneri

Bacterial non-specific acid phosphatases normally catalyze the dephosphorylation of a variety of substrates. As shown previously the enzymes from Shigella flexneri and Salmonella enterica are also able to catalyze the phosphorylation of inosine to inosine monophosphate and D-glucose to D-glucose 6-phosphate (D-G6P) using cheap pyrophosphate as the phosphate donor. After optimization high yields (95%) are achieved in the latter reaction and we show here that it is possible to use these enzymes in a preparative manner. This prompted us to investigate by using 31P NMR and HPLC also the phosphorylation of a broad range of carbohydrates and alcohols. Many cyclic carbohydrates are phosphorylated in a regioselective manner. Non-cyclic carbohydrates are phosphorylated as well. Phosphorylation of linear alcohols, cyclic and aromatic alcohols is also possible. In all cases the acid phosphatase from Shigella prefers a primary alcohol function above a secondary one. We conclude that these enzymes are an attractive alternative to existing chemical and enzymatic methods in the phosphorylation of a broad range of compounds.

Plasmid relaxation induced by copper metalated diglycine conjugates under heterogeneous reaction conditions

This paper reports synthesis and plasmid modification activities of a new class of insoluble copper-metalated diglycine conjugates, containing aliphatic linkers of varying length. Besides providing significant rate enhancement for model phosphate ester cl