106032-25-1

Basic information

• Product Name: 1-Benzyloxycarbonyl-4-methyl-5-oxoperhydroazocine
• Synonyms: 1-Benzyloxycarbonyl-4-methyl-5-oxoperhydroazocine
• CAS NO: 106032-25-1
• Molecular Weight: 275.348
• Mol File: 106032-25-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 1-Benzyloxycarbonyl-4-methyl-5-oxoperhydroazocine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Benzyloxycarbonyl-4-methyl-5-oxoperhydroazocine(106032-25-1)
• EPA Substance Registry System: 1-Benzyloxycarbonyl-4-methyl-5-oxoperhydroazocine(106032-25-1)

Safety Data

• Hazardous Substances Data: 106032-25-1(Hazardous Substances Data)

Upstream product

• 61995-20-8 N-(benzyloxycarbonyl)-3-piperidone 
• 83621-33-4 benzyl 4-oxoazepane-1-carboxylate 
• 88177-13-3 N-Benzyl-2,2,2-trifluoro-N-[2-(1-methyl-2,5-dioxo-cyclopentyl)-ethyl]-acetamide 
• 88187-36-4 1-Benzyl-6-methyl-azocane-2,5-dione 
• 25070-76-2 benzyl diallylcarbamate 
• 80662-83-5 1-Benzyloxycarbonyl-5-oxoperhydroazocine 
• 74-88-4 methyl iodide 
• 88187-38-6 1-Benzyl-5,5-dimethoxy-4-methyl-azocane 
• 501-53-1 benzyl chloroformate 
• 76466-51-8 1-Methyl-1,2,3,5,6,7-hexahydro-pyrrolizinylium; perchlorate 

Downstream Products

• 88187-28-4 4-Acetoxy-6-methyl-5-oxo-azocane-1-carboxylic acid benzyl ester 
• 88187-30-8 4-Hydroxy-6-methyl-5-oxo-azocane-1-carboxylic acid benzyl ester 
• 88187-39-7 4-Methyl-5-oxo-6-(tetrahydro-pyran-2-yloxy)-azocane-1-carboxylic acid benzyl ester 

Relevant articles and documents

Catalytic Ring Expansions of Cyclic Alcohols Enabled by Proton-Coupled Electron Transfer

We report here a catalytic method for the modular ring expansion of cyclic aliphatic alcohols. In this work, proton-coupled electron transfer activation of an allylic alcohol substrate affords an alkoxy radical intermediate that undergoes subsequent C-C bond cleavage to furnish an enone and a tethered alkyl radical. Recombination of this alkyl radical with the revealed olefin acceptor in turn produces a ring-expanded ketone product. The regioselectivity of this C-C bond-forming event can be reliably controlled via substituents on the olefin substrate, providing a means to convert a simple N-membered ring substrate to either n+1 or n+2 ring adducts in a selective fashion.

Ring transformation of 1,2,3,5,6,7-hexahydropyrrolizinium perchlorates into 1-substituted 5-oxoperhydroazocines

A facile ring transformation of 1,2,3,5,6,7-hexahydropyrrolizinium perchlorates (1 and 2) to 1-substituted 5-oxoperhydroazocines (5) is described. The spectroscopic and chemical properties of these products are also presented.

AN EFFICIENT SYNTHESIS OF MEDIUM-SIZED KETOLACTAMS THROUGH CONTROLLED CRISSCROSS ANNULATION: A SYNTHESIS OF (+/-)-DIHYDRODESOXYOTONECINE

Controlled crisscross annulation was applied to the synthesis of (+/-)-dihydrodesoxyotonecine, a degradation product of secopyrrolizidine alkaloids.