1060691-74-8Relevant articles and documents
Novel aminopeptidase N inhibitors derived from 1,3,4-thiadiazole scaffold
Tu, GuoGang,Li, ShaoHua,Huang, HuiMing,Li, Gang,Xiong, Fang,Mai, Xi,Zhu, HuaWei,Kuang, BinHai,Xu, Wen Fang
, p. 6663 - 6668 (2008/12/22)
The aminopeptidase N (APN/CD13), overexpressed in tumor cells, plays a critical role in angiogenesis. In this study, we report the synthesis and in vitro enzyme inhibition assay of 1,3,4-thiadiazole scaffold compounds. These new compounds have potent inhi