106157-82-8

Basic information

• Product Name: Ethanone,1-(2-amino-4-pyrimidinyl)-
• Synonyms: Ethanone,1-(2-amino-4-pyrimidinyl)-;Ethanone, 1-(2-amino-4-pyrimidinyl)- (9CI);2-AMino-4-acetylpyriMidine;1-(2-amino-4-pyrimidinyl)Ethanone
• CAS NO: 106157-82-8
• Molecular Formula: C₆H₇N₃O
• Molecular Weight: 137.13928
• Product Categories: PYRIMIDINE;ACETYLGROUP
• Mol File: 106157-82-8.mol
• Article Data: 7

Chemical Properties

• Melting Point: 148-149 °C(Solv: ethanol (64-17-5))
• Boiling Point: 351.345°C at 760 mmHg
• Flash Point: 166.288°C
• Appearance: /
• Density: 1.25g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.584
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 1.70±0.10(Predicted)
• CAS DataBase Reference: Ethanone,1-(2-amino-4-pyrimidinyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone,1-(2-amino-4-pyrimidinyl)-(106157-82-8)
• EPA Substance Registry System: Ethanone,1-(2-amino-4-pyrimidinyl)-(106157-82-8)

Safety Data

• Hazardous Substances Data: 106157-82-8(Hazardous Substances Data)

Usage

General Description

Ethanone, 1-(2-amino-4-pyrimidinyl)- is a chemical compound with the molecular formula C7H8N4O. It is a ketone compound with an attached pyrimidine ring, and it contains an amino group at the second carbon position of the pyrimidine ring. Ethanone,1-(2-amino-4-pyrimidinyl)- may have potential applications in various chemical and pharmaceutical processes, possibly in the synthesis of other organic compounds or as a component in medicinal or agricultural products. Its specific properties and uses would depend on the context and the intended application in various industries.

InChI:InChI=1/C6H7N3O/c1-4(10)5-2-3-8-6(7)9-5/h2-3H,1H3,(H2,7,8,9)

Upstream product

• 106157-85-1 4-Acetyl-2-aminopyrimidine dimethylketal 
• 106157-94-2 5-Dimethylamino-3-oxo-4-penten-2-one-3-dimethylketal 
• 106157-94-2 1-(dimethylamino)-4,4-dimethoxypent-1-en-3-one 

Downstream Products

• 106157-91-9 1-(2-amino-pyrimidin-4-yl)-2-bromo-ethanone hydrobromide 

Relevant articles and documents

AMINO-HETEROARYL DERIVATIVES AS HCN BLOCKERS

The invention relates to amino-heteroaryl derivatives having the general Formula I or a pharmaceutically acceptable salt thereof, to pharmaceutical compositions comprising the same, as well as to the use of these derivatives for the treatment of pain, such as neuropathic pain or inflammatory pain.

N-substituted pyrrolopyridinones active as kinase inhibitors

Compounds represented by formula (I) wherein A, R1, R2, R3, R4, R5, and R6 are as defined in the specification, pharmaceutical compositions thereof, and methods of use thereof.

PYRIMIDYLPYRROLE DERIVATIVES ACTIVE AS KINASE INHIBITORS

Pyrimidylpyrrole derivatives of formula (1) and pharmaceutically acceptable salts thereof, as defined in the specification, process for their preparation and pharmaceutical compositions comprising them are disclosed; the compounds of the invention may be