106162-46-3

Basic information

• Product Name: N-im-tosyl-L-histidyl>-5(S)-amino-4(S)-hydroxy-2(S)-isopropyl-7-methyloctanoyl>-L-isoleucyl>-2-pyridylmethylamine
• Synonyms: N-im-tosyl-L-histidyl>-5(S)-amino-4(S)-hydroxy-2(S)-isopropyl-7-methyloctanoyl>-L-isoleucyl>-2-pyridylmethylamine
• CAS NO: 106162-46-3
• Molecular Weight: 826.07
• Mol File: 106162-46-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-im-tosyl-L-histidyl>-5(S)-amino-4(S)-hydroxy-2(S)-isopropyl-7-methyloctanoyl>-L-isoleucyl>-2-pyridylmethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-im-tosyl-L-histidyl>-5(S)-amino-4(S)-hydroxy-2(S)-isopropyl-7-methyloctanoyl>-L-isoleucyl>-2-pyridylmethylamine(106162-46-3)
• EPA Substance Registry System: N-im-tosyl-L-histidyl>-5(S)-amino-4(S)-hydroxy-2(S)-isopropyl-7-methyloctanoyl>-L-isoleucyl>-2-pyridylmethylamine(106162-46-3)

Safety Data

• Hazardous Substances Data: 106162-46-3(Hazardous Substances Data)

Upstream product

• 103322-68-5 N-α-(tert-butyloxycarbonyl)-L-isoleucyl>-2-pyridylmethylamine 
• 97920-16-6 N-L-isoleucyl-2-pyridylmethylamine 
• 13139-16-7 N-(tert-butyloxycarbonyl)-L-isoleucine 
• 3731-51-9 2-(Aminomethyl)pyridine 
• 35899-43-5 Boc-His(Tos)-OH 
• 103882-43-5 (2S,4S,5S)-5-Amino-4-hydroxy-2-isopropyl-7-methyl-octanoic acid {(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butyl}-amide; hydrochloride 

Downstream Products

• 134209-72-6 dansyl-Phe-His-LVA-Ile-Amp 
• 134209-73-7 dansyl-Phe-His(Tos)-LVA-Ile-Amp 
• 126082-58-4 (phenylacetyl)-N^im-tosyl-L-histidyl-5(S)-amino-4(S)-hydroxy-2(S)-isopropyl-7-(methyloctanoyl)-L-isoleucyl-2-pyridylmethylamine 
• 103352-48-3 (2S,4S,5S)-4-Hydroxy-5-[(S)-3-(1H-imidazol-4-yl)-2-(2-phenoxy-acetylamino)-propionylamino]-2-isopropyl-7-methyl-octanoic acid {(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butyl}-amide 
• 126082-57-3 (phenylacetyl)-L-histidyl-5(S)-amino-4(S)-hydroxy-2(S)-isopropyl-7-(methyloctanoyl)-L-isoleucyl-2-pyridylmethylamine 
• 103372-31-2 (2S,4S,5S)-5-{(S)-2-Amino-3-[1-(toluene-4-sulfonyl)-1H-imidazol-4-yl]-propionylamino}-4-hydroxy-2-isopropyl-7-methyl-octanoic acid {(1S,2S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butyl}-amide 
• 103372-31-2 (2S,4S,5S)-5-{(S)-2-Amino-3-[1-(toluene-4-sulfonyl)-1H-imidazol-4-yl]-propionylamino}-4-hydroxy-2-isopropyl-7-methyl-octanoic acid {(S)-2-methyl-1-[(pyridin-2-ylmethyl)-carbamoyl]-butyl}-amide 

Relevant articles and documents

Renin Inhibitory Peptides. A β-Aspartyl Residue as a Replacement for the Histidyl Residue at the P-2 Site

In an effort to decrease the size and to increase the hydrophilicity of the previously prepared renin inhibitory peptides, it was postulated that one might be able to take advantage of the polar Thr-84 on the flap region of the enzyme renin by potential h