1062642-64-1Relevant articles and documents
Zwitterionic uracil derivatives as potent GnRH receptor antagonists with improved pharmaceutical properties
Regan, Colin F.,Guo, Zhiqiang,Chen, Yongsheng,Huang, Charles Q.,Chen, Mi,Jiang, Wanlong,Rueter, Jaimie K.,Coon, Timothy,Chen, Chen,Saunders, John,Brown, Michael S.,Betz, Steve F.,Struthers, R. Scott,Yang, Chun,Wen, Jenny,Madan, Ajay,Zhu, Yun-Fei
scheme or table, p. 4503 - 4507 (2009/04/06)
A novel series of potent zwitterionic uracil GnRH antagonists were discovered that showed reduced liability for CYP3A4 enzyme inhibition.