106270-21-7

Basic information

• Product Name: 4-benzoylamino-5-oxo-hexanoic acid
• CAS NO: 106270-21-7
• Molecular Weight: 249.266
• Mol File: 106270-21-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-benzoylamino-5-oxo-hexanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-benzoylamino-5-oxo-hexanoic acid(106270-21-7)
• EPA Substance Registry System: 4-benzoylamino-5-oxo-hexanoic acid(106270-21-7)

Safety Data

• Hazardous Substances Data: 106270-21-7(Hazardous Substances Data)

Upstream product

• 54819-34-0 4-Benzoylamino-5-oxo-hexanoic acid methyl ester 
• 6094-36-6 N-benzoylglutamic acid 
• 108-24-7 acetic anhydride 
• 14307-84-7 N-benzoyl-L-glutamic acid γ-methyl ester 

Downstream Products

• 54819-34-0 4-Benzoylamino-5-oxo-hexanoic acid methyl ester 

Relevant articles and documents

Discovery of a novel class of 1,3-dioxane-2-carboxylic acid derivatives as subtype-selective peroxisome proliferator-activated receptor α (PPARα) agonists

A new series of 1,3-dioxane-2-carboxylic acid derivatives was synthesized and evaluated for agonist activity at human peroxisome proliferator-activated receptor (PPAR) subtypes. Structure-activity relationship studies led to the identification of 2-methyl-c-5-[4-(5-methyl-2-phenyl-1,3-oxazol-4-yl)butyl]-1,3-dioxane-r-2-carboxylic acid 4b as a potent PPARα agonist with high subtype selectivity at human receptor subtypes. This compound exhibited a substantial hypolipidemic effect in type 2 diabetic KK-Ay mice.