106283-19-6

Basic information

• Product Name: VIRIDICACID
• Synonyms: VIRIDICACID
• CAS NO: 106283-19-6
• Molecular Formula: C₂₄H₃₀N₄O₅
• Molecular Weight: 454.5188
• Mol File: 106283-19-6.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 623.9°C at 760 mmHg
• Flash Point: 331.1°C
• Appearance: /
• Density: 1.266g/cm³
• Vapor Pressure: 1.98E-16mmHg at 25°C
• Refractive Index: 1.622
• CAS DataBase Reference: VIRIDICACID(CAS DataBase Reference)
• NIST Chemistry Reference: VIRIDICACID(106283-19-6)
• EPA Substance Registry System: VIRIDICACID(106283-19-6)

Safety Data

• Hazardous Substances Data: 106283-19-6(Hazardous Substances Data)

Usage

InChI:InChI=1/C24H30N4O5/c1-15(2)21(27(5)19-13-9-7-11-17(19)24(32)33)23(31)28(20(29)14-25)22(30)16-10-6-8-12-18(16)26(3)4/h6-13,15,21H,14,25H2,1-5H3,(H,32,33)/t21-/m0/s1

Upstream product

• 3339-44-4 methyl N-methyl-L-valinate hydrochloride 
• 13734-41-3 t-Boc-L-valine 
• 45170-31-8 Boc-N-Me-Val-OH 
• 1418290-22-8 methyl 2-(2-(2-(2-(dimethylamino)benzamido)-N-methylacetamido)-3-methyl-butanamido)benzoate 
• 1418290-37-5 N-(2,4-dimethoxybenzyl)-2-(dimethylamino)-N-(2-oxo-2-((2,4,4-trimethoxybutyl)amino)ethyl)benzamide 
• 748092-23-1 2-(2-(dimethylamino)benzamido)acetic acid 
• 66715-31-9 o-methoxycarbonylphenylisonitrile 
• 1418290-20-6 benzyl 2-(2-(dimethylamino)benzamido)acetate 
• 118-48-9 isatoic anhydride 
• 610-16-2 N,N-dimethylanthranilic acid 
• 1418290-15-9 (S)-benzyl 2-(2-(2-(2-(dimethylamino)benzamido)-N-methylacetamido)-3-methylbutanamido)benzoate 
• 1418290-19-3 (S)-benzyl 2-(2-(2-amino-N-methylacetamido)-3-methylbutanamido)benzoate 2,2,2-trifluoroacetate 
• 1418290-17-1 (S)-benzyl 2-(2-(2-(tert-butoxycarbonylamino)-N-methylacetamido)-3-methyl-butanamido)benzoate 
• 1418290-16-0 (S)-2-(2-(tert-butoxycarbonylamino)-N-methylacetamido)-3-methylbutanoic acid 

Relevant articles and documents

The multicomponent approach to N-methyl peptides: Total synthesis of antibacterial (-)-viridic acid and analogues

Two syntheses of natural viridic acid, an unusual triply N-methylated peptide with two anthranilate units, are presented. The first one is based on peptide-coupling strategies and affords the optically active natural product in 20% overall yield over six steps. A more economical approach with only four steps leads to the similarly active racemate by utilizing a Ugi four-component reaction (Ugi-4CR) as the key transformation. A small library of viridic acid analogues is readily available to provide first SAR insight. The biological activities of the natural product and its derivatives against the Gram-negative bacterium Aliivibrio fischeri were evaluated.