106296-25-7

Basic information

• Product Name: Benzoic acid, 2,5-bis(phenylmethoxy)-, methyl ester
• CAS NO: 106296-25-7
• Molecular Formula: C22H20O4
• Molecular Weight: 348.398
• Mol File: 106296-25-7.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2,5-bis(phenylmethoxy)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2,5-bis(phenylmethoxy)-, methyl ester(106296-25-7)
• EPA Substance Registry System: Benzoic acid, 2,5-bis(phenylmethoxy)-, methyl ester(106296-25-7)

Safety Data

• Hazardous Substances Data: 106296-25-7(Hazardous Substances Data)

Upstream product

• 2150-46-1 Methyl 2,5-dihydroxybenzoate 
• 100-39-0 benzyl bromide 
• 186581-53-3 diazomethane 
• 67127-91-7 2,5-bis(benzyloxy)benzoic acid 

Downstream Products

• 106296-26-8 2,5-dibenzyloxybenzamide 
• 106295-99-2 2-(2,5-Bis-benzyloxy-benzyl)-malonic acid diethyl ester 
• 106296-00-8 2-(2,5-Bis-benzyloxy-benzyl)-malonic acid 
• 106296-13-3 5-(2,5-Bis-benzyloxy-phenyl)-pentanoic acid 
• 106296-05-3 3-(2,5-Bis-benzyloxy-phenyl)-propionic acid methyl ester 
• 106296-07-5 4-(2,5-Bis-benzyloxy-phenyl)-butyronitrile 
• 78302-95-1 3-(2,5-Bis-benzyloxy-phenyl)-propionyl chloride 
• 78302-94-0 3-(2,5-bis(benzyloxy)phenyl)propanoic acid 
• 79054-90-3 3-(2,5-Bis-benzyloxy-phenyl)-propan-1-ol 
• 106295-98-1 2,5-dibenzyloxybenzyl bromide 
• 529-49-7 gentitein 
• 1043-08-9 osajaxanthone 
• 900501-63-5 (2,5-dihydroxyphenyl)(2,4,6-trimethoxyphenyl)methanone 
• 900501-59-9 (2,5-dibenzyloxyphenyl)(2,4,6-trimethoxyphenyl)methanone 

Relevant articles and documents

Metal-free Synthesis of Spiro-2,2′-benzo[b]furan-3,3′-ones via PhI(OAc)2-Mediated Cascade Spirocyclization

Treating the benzyl protected 3-hydroxy-1,3-bis(2-hydroxyphenyl)prop-2-en-1-ones solely with PhI(OAc)2 (PIDA) in DCE at room temperature readily furnished the seldom studied spiro-2,2′-benzo[b]furan-3,3′-ones in satisfactory to excellent yields. The hypervalent iodine reagent enables the metal-free cascade spirocyclization resulting in the dual oxidative C?O bond formation. (Figure presented.).

Facile synthesis of 1,3,7-trihydroxyxanthone and its regioselective coupling reactions with prenal: Simple and efficient access to osajaxanthone and nigrolineaxanthone F

A facile five-step synthesis of naturally occurring 1,3,7- trihydroxyxanthone has been described starting from 1,3,5-trimethoxybenzene via NBS-induced nuclear bromination, lithiation followed by an in situ benzoylation with methyl 2,5-dibenzyloxybenzoate, selective deprotection of the two benzyl groups, base-catalyzed intramolecular cyclization, and demethylations pathway with 62% overall yield. The regioselective coupling reactions of 1,3,7-trihydroxyxanthone with prenal in the presence of calcium hydroxide at room temperature and under thermal conditions at 140-150 °C have been demonstrated to exclusively obtain the natural products osajaxanthone in 15% yield and nigrolineaxanthone F in 98% yield, respectively.

Synthetic aci-Reductones: 3,4-Dihydroxy-2H-1-benzopyran-2-ones and Their cis- and trans-4a,5,6,7,8,8a-Hexahydro Diastereomers. Antiaggregatory, Antilipidemic, and Redox Properties Compared to Those of the 4-Substituted 2-Hydroxytetronic Acids

Synthetic procedures for the elaboration of aci-reductones belonging to the 6- or 7-mono- or bis-substituted-3,4-dihydroxy-2H-1-benzopyran-2-ones (6 - 10) and their cis- and trans-4a,5,6,7,8,8a-hexahydro diastereomers (11, 12) are described.Hexahydrobenzo