106350-96-3Relevant articles and documents
Stereochemistry in the Hydrogenation of Steroidal (22R)- and (22S)-Δ24-26,22-Lactones
Iwadate, Hiroshi,Gamoh, Keiji,Fujimoto, Yoshinori,Ikekawa, Nobuo
, p. 2061 - 2065 (2007/10/02)
Catalytic hydrogenation of the (22R)-unsaturated lactone 8 and its (22S)-epimer 9 afforded stereoselectively the (22R,24R)-saturated lactone 10 and the (22S,24S)-isomer 11, respectively.The C-24 stereochemistry of the hydrogenated products was determined by their conversion into 24-ethylcholesterols.Keywords - stereoselective hydrogenation; stereoidal lactone; sitosterol; clionasterol