1064288-24-9 Usage
Description
(E)-1-(3-hydroxy-4-(MorpholinoMethyl)phenyl)-3-(pyridin-4-yl)prop-2-en-1-one is a complex chemical compound characterized by its unique molecular structure. It features a hydroxyl group and a morpholinomethyl group attached to a phenyl ring, along with a pyridinyl group connected to a propenone moiety. This structural composition endows the compound with potential applications in medicinal chemistry, where its specific features may contribute to significant biological activities.
Uses
Used in Pharmaceutical Industry:
(E)-1-(3-hydroxy-4-(MorpholinoMethyl)phenyl)-3-(pyridin-4-yl)prop-2-en-1-one is used as a potential active pharmaceutical ingredient for the development of new drugs. Its unique molecular structure, which includes a hydroxyl group, a morpholinomethyl group, and a pyridinyl group, may offer valuable properties for targeting specific biological pathways or receptors, thus contributing to the treatment or management of various diseases.
Used in Chemical Research:
In the field of chemical research, (E)-1-(3-hydroxy-4-(MorpholinoMethyl)phenyl)-3-(pyridin-4-yl)prop-2-en-1-one serves as a valuable compound for studying its reactivity, stability, and potential interactions with other molecules. Understanding these properties can lead to the discovery of new reactions or the development of novel synthetic methods, further expanding the compound's utility in chemical synthesis and application.
Used in Drug Design and Development:
(E)-1-(3-hydroxy-4-(MorpholinoMethyl)phenyl)-3-(pyridin-4-yl)prop-2-en-1-one is used as a starting material or a key intermediate in the design and synthesis of new drugs. Its structural features may be exploited to create molecules with improved pharmacokinetic and pharmacodynamic properties, potentially leading to more effective and safer therapeutic agents.
Check Digit Verification of cas no
The CAS Registry Mumber 1064288-24-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,6,4,2,8 and 8 respectively; the second part has 2 digits, 2 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1064288-24:
(9*1)+(8*0)+(7*6)+(6*4)+(5*2)+(4*8)+(3*8)+(2*2)+(1*4)=149
149 % 10 = 9
So 1064288-24-9 is a valid CAS Registry Number.
1064288-24-9Relevant articles and documents
Design, synthesis, and biological evaluation of Mannich bases of heterocyclic chalcone analogs as cytotoxic agents
Reddy, M. Vijaya Bhaskar,Su, Chung-Ren,Chiou, Wen-Fei,Liu, Yi-Nan,Chen, Rosemary Yin-Hwa,Bastow, Kenneth F.,Lee, Kuo-Hsiung,Wu, Tian-Shung
, p. 7358 - 7370 (2008/12/22)
The chalcone skeleton (1,3-diphenyl-2-propen-1-one) is a unique template that is associated with various biological activities. We synthesized Mannich bases of heterocyclic chalcones (9-47) using a one-step Claisen-Schmidt condensation of heterocyclic aldehydes with Mannich bases of acetophenones, and tested the target compounds for cytotoxicity against three human cancer cell lines (prostate, PC-3; breast, MCF-7; nasopharynx, KB) and a multi-drug resistant subline (KB-VIN). Out of the 39 chalcones synthesized, 31 compounds showed potent activity against at least one cell line with IC50 values ranging from 0.03 to 3.80 μg/mL. Structure-activity relationships (SAR) are also discussed.
