1064288-29-4 Usage
Description
(E)-1-(3-hydroxy-2,4-bis(MorpholinoMethyl)phenyl)-3-(pyridin-2-yl)prop-2-en-1-one is a complex chemical compound characterized by its unique molecular structure. It features a phenyl ring with two morpholinomethyl groups, a pyridinyl group, and a propenone moiety. The presence of a hydroxyl group on the phenyl ring imparts hydrophilic properties to the molecule, while the pyridinyl group suggests potential biological activity, as pyridine derivatives are known for their diverse pharmacological properties. The intricate design of this compound points towards its possible applications in the field of medicinal chemistry, particularly in drug discovery and development. Further investigation is required to comprehensively understand its chemical and biological characteristics.
Uses
Used in Pharmaceutical Industry:
(E)-1-(3-hydroxy-2,4-bis(MorpholinoMethyl)phenyl)-3-(pyridin-2-yl)prop-2-en-1-one is used as a potential candidate in drug discovery for its unique molecular structure and the presence of pharmacologically active groups. (E)-1-(3-hydroxy-2,4-bis(MorpholinoMethyl)phenyl)-3-(pyridin-2-yl)prop-2-en-1-one's hydrophilic nature and pyridinyl group may contribute to its interaction with biological targets, making it a promising candidate for the development of new therapeutic agents.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (E)-1-(3-hydroxy-2,4-bis(MorpholinoMethyl)phenyl)-3-(pyridin-2-yl)prop-2-en-1-one is utilized as a subject of study to explore its chemical properties and potential biological activities. Understanding the compound's interactions with various biological targets can lead to the identification of new drug targets and the development of novel therapeutic strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 1064288-29-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,6,4,2,8 and 8 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1064288-29:
(9*1)+(8*0)+(7*6)+(6*4)+(5*2)+(4*8)+(3*8)+(2*2)+(1*9)=154
154 % 10 = 4
So 1064288-29-4 is a valid CAS Registry Number.
1064288-29-4Relevant articles and documents
Design, synthesis, and biological evaluation of Mannich bases of heterocyclic chalcone analogs as cytotoxic agents
Reddy, M. Vijaya Bhaskar,Su, Chung-Ren,Chiou, Wen-Fei,Liu, Yi-Nan,Chen, Rosemary Yin-Hwa,Bastow, Kenneth F.,Lee, Kuo-Hsiung,Wu, Tian-Shung
, p. 7358 - 7370 (2008/12/22)
The chalcone skeleton (1,3-diphenyl-2-propen-1-one) is a unique template that is associated with various biological activities. We synthesized Mannich bases of heterocyclic chalcones (9-47) using a one-step Claisen-Schmidt condensation of heterocyclic aldehydes with Mannich bases of acetophenones, and tested the target compounds for cytotoxicity against three human cancer cell lines (prostate, PC-3; breast, MCF-7; nasopharynx, KB) and a multi-drug resistant subline (KB-VIN). Out of the 39 chalcones synthesized, 31 compounds showed potent activity against at least one cell line with IC50 values ranging from 0.03 to 3.80 μg/mL. Structure-activity relationships (SAR) are also discussed.
