106509-83-5

Basic information

• Product Name: dimethyl 2-(4-bromophenylamino)maleate
• Synonyms: dimethyl 2-(4-bromophenylamino)maleate
• CAS NO: 106509-83-5
• Molecular Weight: 314.136
• Mol File: 106509-83-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: dimethyl 2-(4-bromophenylamino)maleate(CAS DataBase Reference)
• NIST Chemistry Reference: dimethyl 2-(4-bromophenylamino)maleate(106509-83-5)
• EPA Substance Registry System: dimethyl 2-(4-bromophenylamino)maleate(106509-83-5)

Safety Data

• Hazardous Substances Data: 106509-83-5(Hazardous Substances Data)

Upstream product

• 762-42-5 dimethyl acetylenedicarboxylate 
• 106-40-1 4-bromo-aniline 

Relevant articles and documents

Copper(I)-catalyzed one-pot synthesis of highly functionalized pyrrolidines from sulfonyl azides, alkynes, and dimethyl 2-(phenylamino)maleate

An efficient one-pot synthesis of highly functionalized pyrrolidines by using sulfonyl azides, alkynes, and dimethyl 2-(phenylamino)maleate catalyzed by copper(I)-Y zeolite under mild reaction conditions was investigated. This cascade process involves an azide-alkyne [3+2] cycloaddition/ring rearrangement/ketenimine formation/intermolecular nucleophilic addition cascade and consequent intramolecular cyclization followed by [1,3]-H shift. The important advantage of this methodology, which allows selective intramolecular nucleophilic attack of the generated ketenimine carbanion on an ester moiety for the first time, is that the starting materials can be easily prepared.