106656-55-7Relevant articles and documents
NMR Spectra and Stereochemistry of 2-(Piperidin-2-ylmethyl)cycloalkanols
Begley, Michael J.,Crabb, Trevor A.,Roch, Olive G.
, p. 292 - 296 (1986)
2-(Piperidin-2-ylmethyl)cycloalkanols have been synthesized by the reaction between 2-picolyllithium and cycloalkene oxides, followed by catalytic hydrogenation of the resulting 2-(pyridin-2-ylmethyl)cycloalkanols.The configurations of the 2-(piperidin-2-yl-methyl)cycloalkanols were assigned by comparing their 13C and 1H NMR parameters with those of 2-(piperidin-2-ylmethyl)cyclohexanols of known (x-ray) configuration.