106673-42-1Relevant articles and documents
The Synthesis and Ring Opening Reactions of 1,10-Disubstituted-2,3 (R,R + S,S) Epoxy Decanes - A Route to Heterocyclic Prostaglandin Analogues.
Grayshan, Roger,Keal, Colin A.,Sackville, Michael A.
, p. 2501 - 2542 (2007/10/02)
Synthetic routes leading to (E)-1,10-di-derivatised dec-2-enes are outlined; in particular the syntheses of (E)-1-benzyloxy-10-methoxyethoxymethoxydec-2-ene and (E)-10-benzyloxy-1-methoxyethoxymethoxydec-2-ene are described.Ring opening reactions between 2-lithio-1,3-dithiane and the oxiranes derived from the above two decenes were studied and the ratio of isomeric dithianyl alcohols produced was shown to be influenced by the nature of the C-1 hydroxyl protecting group.These results are discussed in terms of co-ordinative interactions between the lithiodithiane reagent and the complementary oxygens of the substituted oxiranes.