106711-53-9

Basic information

• Product Name: C₁₈H₂₄O₅
• Synonyms: C₁₈H₂₄O₅
• CAS NO: 106711-53-9
• Molecular Weight: 320.386
• Mol File: 106711-53-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₈H₂₄O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₂₄O₅(106711-53-9)
• EPA Substance Registry System: C₁₈H₂₄O₅(106711-53-9)

Safety Data

• Hazardous Substances Data: 106711-53-9(Hazardous Substances Data)

Upstream product

• 18439-45-7 3-O-Benzyl-6-desoxy-1,2-O-isopropyliden-α-D-gluco-hexofuranose 
• 931-94-2 1,1-dimethoxycyclopentane 
• 106711-50-6 3-O-Benzyl-6-deoxy-D-glucose 

Downstream Products

• 106711-61-9 (2S,3R,4S,5R,6R)-4-Benzyloxy-2-{(2S,3R,4S,5R,6R)-4-benzyloxy-5-hydroxy-6-methyl-2-[((E)-propenyl)oxy]-tetrahydro-pyran-3-yloxy}-6-methyl-tetrahydro-pyran-3,5-diol 
• 106711-61-9 (2S,3R,4S,5R,6R)-4-Benzyloxy-2-{(2R,3R,4S,5R,6R)-4-benzyloxy-5-hydroxy-6-methyl-2-[((E)-propenyl)oxy]-tetrahydro-pyran-3-yloxy}-6-methyl-tetrahydro-pyran-3,5-diol 
• 106711-55-1 Acetic acid (2R,3R,4R,5R,6S)-6-allyloxy-4-benzyloxy-5-hydroxy-2-methyl-tetrahydro-pyran-3-yl ester 
• 106711-56-2 Acetic acid (2R,3R,4R,5R,6R)-6-allyloxy-4-benzyloxy-5-hydroxy-2-methyl-tetrahydro-pyran-3-yl ester 
• 131681-83-9 C₅₈H₉₄O₁₇Si₃ 
• 106711-70-0 C₅₈H₉₄O₁₇Si₃ 
• 109922-65-8 C₄₇H₅₈O₁₇ 
• 109922-65-8 C₄₇H₅₈O₁₇ 
• 63166-73-4 (+)-α-phyllanthoside 
• 63166-73-4 Phyllanthoside 
• 106711-62-0 C₄₇H₈₀O₉Si₃ 
• 106711-62-0 C₄₇H₈₀O₉Si₃ 
• 106711-63-1 Formic acid (2R,3R,4R,5R,6R)-4-benzyloxy-3-((2S,3R,4S,5R,6R)-4-benzyloxy-6-methyl-3,5-bis-triethylsilanyloxy-tetrahydro-pyran-2-yloxy)-6-methyl-5-triethylsilanyloxy-tetrahydro-pyran-2-yl ester 
• 134311-84-5 Formic acid (2S,3R,4R,5R,6R)-4-benzyloxy-3-((2S,3R,4S,5R,6R)-4-benzyloxy-6-methyl-3,5-bis-triethylsilanyloxy-tetrahydro-pyran-2-yloxy)-6-methyl-5-triethylsilanyloxy-tetrahydro-pyran-2-yl ester 

Relevant articles and documents

Phyllanthoside-Phyllanthostatin Synthetic Studies. 8. Total Synthesis of (+)-Phyllanthoside. Development of the Mitsunobu Glycosyl Ester Protocol

The first total syntheses of the antineoplastic glycoside (+)-phyllanthoside (1) and the parent disaccharide (-)-phyllanthose (5) have been achieved. Stereoselective Koenigs-Knorr coupling of two 6-deoxyglucose derivatives, bromide 54 and alcohol 55, generated the uncommon 1′ → 2β glycosidic linkage of (-)-phyllanthose. A stereochemically convergent Mitsunobu reaction of protected disaccharide 87 with aglycon carboxylic acid 80, prepared via asymmetric synthesis, then led to 1 of high enantiomeric purity. The Mitsunobu procedure comprises an efficient general method for stereospecific assembly of β-glycosyl esters.